Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | CXCR4 | P61073 | 9/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | CCR2 | P41597 | 1/20 | 0.60 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL674847 | 0.97 | CXCR4 (0.65) | SIGMAR1CXCR4TDP1PRMT6MEN1 | |
| SCHEMBL674945 | 0.90 | CXCR4 (0.75) | SIGMAR1CXCR4TDP1PRMT6MEN1 | |
| SCHEMBL1259323 | 0.88 | CXCR4 (0.67) | SIGMAR1CXCR4TDP1PRMT6MEN1 | |
| SCHEMBL17929341 | 0.88 | CXCR4 (0.72) | SIGMAR1CXCR4TDP1PRMT6MEN1 | |
| SCHEMBL675084 | 0.88 | CXCR4 (0.67) | SIGMAR1CXCR4TDP1PRMT6MEN1 | |
| SCHEMBL1259602 | 0.88 | SIGMAR1 (0.71) | SIGMAR1CXCR4TDP1PRMT6MEN1 | |
| SCHEMBL21961925 | 0.88 | SIGMAR1 (0.71) | SIGMAR1CXCR4TDP1PRMT6MEN1 | |
| Bromide SCHEMBL5675524 | 0.87 | CXCR4 (0.71) | SIGMAR1CXCR4TDP1PRMT6MEN1 | |
| SCHEMBL27300143 | 0.87 | SIGMAR1 (0.77) | SIGMAR1CXCR4TDP1MEN1CHRM2 | |
| Bromide SCHEMBL7495511 | 0.86 | CXCR4 (0.68) | SIGMAR1CXCR4TDP1PRMT6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005002522-A2 | COMPOSITIONS AND METHODS FOR TREATING TISSUE ISCHEMIA | CARITAS ST. ELIZABETH'S MEDICAL CENTER OF BOSTON, INC. (US) | 2005-01-13 | — | — | WO | claimed |