Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | HPD | P32754 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310333 | 0.81 | MAOB (0.66) | MAOBMTNR1BMAOAALDH1A1CYP3A4 | |
| SCHEMBL6237392 | 0.81 | NPC1 (0.50) | MAOBNPC1RAB9AMTNR1BHPD | |
| SCHEMBL13034145 | 0.80 | MEN1 (0.53) | MAOBMTNR1BHPDMEN1ALDH1A1 | |
| SCHEMBL31530409 | 0.79 | NPC1 (0.54) | MAOBNPC1RAB9AMTNR1BHPD | |
| SCHEMBL8102862 | 0.79 | NPC1 (0.56) | MAOBNPC1RAB9AHPD | |
| SCHEMBL1313096 | 0.78 | PARP15 (0.58) | MAOBMTNR1BHPDPARP15PARP14 | |
| SCHEMBL5095909 | 0.76 | MAOB (0.44) | MAOBNPC1RAB9AMTNR1BHPD | |
| SCHEMBL14720671 | 0.75 | PDPK1 (0.46) | MAOBMTNR1BMEN1ALDH1A1KMT2A | |
| SCHEMBL6236731 | 0.74 | MAOB (0.57) | MAOBRAB9AGSK3BBACE1MAOA | |
| SCHEMBL12069956 | 0.74 | MEN1 (0.46) | MAOBMTNR1BHPDMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |