Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HPD | P32754 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 9/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14967007 | 0.83 | PDPK1 (0.47) | NPC1RAB9AHPDMAOBKDM1A | |
| SCHEMBL4638691 | 0.83 | HPD (0.56) | NPC1RAB9AHPDMAOB | |
| SCHEMBL13450401 | 0.82 | MAOB (0.60) | MAOBHDAC1HDAC6HDAC5 | |
| SCHEMBL31530409 | 0.81 | NPC1 (0.54) | NPC1RAB9AHPDMAOB | |
| SCHEMBL6237392 | 0.79 | NPC1 (0.50) | NPC1RAB9AHPDMAOB | |
| SCHEMBL14966760 | 0.79 | MAOB (0.49) | NPC1RAB9AMAOB | |
| SCHEMBL27382833 | 0.79 | MAOB (0.48) | HPDMAOBHDAC1HDAC6HDAC5 | |
| SCHEMBL311630 | 0.79 | MAOB (0.65) | NPC1RAB9AMAOB | |
| SCHEMBL29385396 | 0.79 | MAOB (0.65) | NPC1RAB9AMAOB | |
| SCHEMBL6237398 | 0.79 | MAOB (0.57) | NPC1RAB9AHPDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628532-B1 | Fluorobenzole derivatives and mesomorphous medium | MERCK PATENT GMBH (DE) | 2000-01-19 | — | — | EP | disclosed |
| US-5641429-A | STABLE COMPOUNDS HAVING LOW VISCOSITY AND HIGH DIELECTRIC ANISOTROPY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-06-24 | — | — | US | disclosed |
| US-5536442-A | ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-16 | — | — | US | disclosed |
| US-5487845-A | ELECTROOPTICAL DISPLAY ELEMENTS; CHEMICAL, HEAT AND LIGHT STABILITY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-01-30 | — | — | US | disclosed |
| EP-0394906-B1 | Liquid crystalline composition | MERCK PATENT GMBH (DE) | 1995-12-20 | — | — | EP | disclosed |
| EP-0441932-B1 | FLUOROBENZOLE DERIVATIVES AND MESOMORPHOUS MEDIUM | MERCK PATENT GMBH (DE) | 1995-03-15 | — | — | EP | disclosed |
| EP-0628532-A1 | Fluorobenzole derivatives and mesomorphous medium | MERCK PATENT GmbH (DE) | 1994-12-14 | — | — | EP | disclosed |
| EP-0394906-A2 | Liquid crystalline composition | MERCK PATENT GmbH (DE) | 1990-10-31 | — | — | EP | disclosed |