Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31298392 | 1.00 | BACE1 (0.33) | BACE1DPP4RBP4 | |
| SCHEMBL25185127 | 1.00 | BACE1 (0.33) | BACE1DPP4RBP4 | |
| SCHEMBL6233213 | 1.00 | BACE1 (0.33) | BACE1DPP4RBP4 | |
| SCHEMBL31234343 | 0.90 | GRM1 (0.36) | BACE1 | |
| SCHEMBL30404900 | 0.89 | UCHL1 (0.37) | — | |
| SCHEMBL30404541 | 0.89 | UCHL1 (0.37) | — | |
| SCHEMBL31298397 | 0.82 | AGTR2 (0.36) | BACE1 | |
| SCHEMBL22691859 | 0.82 | AGTR2 (0.36) | BACE1 | |
| SCHEMBL25380301 | 0.82 | AGTR2 (0.36) | BACE1 | |
| SCHEMBL30391920 | 0.82 | AGTR2 (0.36) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081840-A1 | KRAS G12C INHIBITORS | FRONTIER MEDICINES CORPORATION (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |