Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.75 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.75 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | GCG | P01275 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.50 |
| ▸ | CFD | P00746 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235803 | 0.83 | FFAR1 (0.60) | FFAR1FFAR4RAB9AGFERSMN1; SMN2 | |
| SCHEMBL14044097 | 0.82 | FFAR1 (0.66) | FFAR1FFAR4RAB9ASMN1; SMN2TSHR | |
| SCHEMBL10018553 | 0.81 | RAB9A (0.69) | FFAR1FFAR4RAB9AGFERSMN1; SMN2 | |
| SCHEMBL6243479 | 0.80 | FFAR1 (0.56) | FFAR1FFAR4RAB9AGFERSMN1; SMN2 | |
| SCHEMBL28408449 | 0.79 | PTGS1 (0.66) | FFAR1FFAR4RAB9AGFERSMN1; SMN2 | |
| SCHEMBL5447986 | 0.79 | FFAR1 (0.84) | FFAR1FFAR4RAB9AGFERSMN1; SMN2 | |
| SCHEMBL6238362 | 0.78 | ABCC4 (0.59) | FFAR1FFAR4ABCC4LMNAGAA | |
| SCHEMBL5446291 | 0.77 | HIF1A (0.69) | FFAR1RAB9AGFERSMN1; SMN2GAA | |
| SCHEMBL16439876 | 0.77 | LMNA (0.80) | FFAR1ABCC4LMNAGAATSHR | |
| SCHEMBL27672046 | 0.76 | ABCC4 (0.61) | FFAR1FFAR4ABCC4LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |