Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ACP3 | P15309 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11138029 | 0.82 | POLB (0.56) | POLBMAPK1NPSR1HPGDALOX15 | |
| SCHEMBL11133869 | 0.82 | POLB (0.56) | POLBMAPK1NPSR1HPGDALOX15 | |
| SCHEMBL6239506 | 0.82 | ALDH1A1 (0.52) | POLBMAPK1NPSR1HPGDALOX15 | |
| SCHEMBL7466891 | 0.82 | POLB (0.56) | POLBMAPK1NPSR1HPGDALOX15 | |
| SCHEMBL6235933 | 0.82 | POLB (0.48) | POLBNPSR1ALOX15MAPTLMNA | |
| SCHEMBL2281034 | 0.81 | POLB (0.68) | POLBMAPK1NPSR1HPGDALOX15 | |
| SCHEMBL17223172 | 0.80 | POLB (0.53) | POLBACP3MAPK1NPSR1HPGD | |
| SCHEMBL19422635 | 0.79 | POLB (0.56) | POLBACP3MAPK1NPSR1HPGD | |
| SCHEMBL13321997 | 0.79 | POLB (0.66) | POLBACP3MAPK1NPSR1HPGD | |
| SCHEMBL2281038 | 0.77 | ACP3 (0.46) | POLBACP3LMNASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003143-A1 | NOVEL POTASSIUM CHANNEL MODULATORS | POSEIDON PHARMACEUTICALS A/S (DK) | 2005-01-13 | — | — | WO | claimed |
| WO-2005003143-A1 | NOVEL POTASSIUM CHANNEL MODULATORS | POSEIDON PHARMACEUTICALS A/S (DK) | 2005-01-13 | — | — | WO | disclosed |