Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10631182 | 0.85 | POLB (0.47) | POLBNPC1MAPTCYP1A2LMNA | |
| SCHEMBL6239506 | 0.83 | ALDH1A1 (0.52) | POLBLMNANPSR1CA12CA1 | |
| SCHEMBL6237835 | 0.82 | POLB (0.59) | POLBMAPTLMNANPSR1GAA | |
| SCHEMBL11140297 | 0.76 | POLB (0.70) | POLBNPC1MAPTNPSR1L3MBTL1 | |
| SCHEMBL10625932 | 0.74 | L3MBTL1 (0.49) | POLBNPC1MAPTLMNANPSR1 | |
| SCHEMBL23357439 | 0.73 | PTPN2 (0.48) | POLBNPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL19638012 | 0.73 | ACP3 (0.58) | MAPTCYP1A2LMNATHRBPMP22 | |
| SCHEMBL914714 | 0.73 | NPC1 (0.48) | POLBNPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL1833136 | 0.72 | L3MBTL1 (0.48) | POLBNPC1MAPTLMNAL3MBTL1 | |
| SCHEMBL5539383 | 0.72 | L3MBTL1 (0.48) | POLBNPC1MAPTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003143-A1 | NOVEL POTASSIUM CHANNEL MODULATORS | POSEIDON PHARMACEUTICALS A/S (DK) | 2005-01-13 | — | — | WO | claimed |
| WO-2005003143-A1 | NOVEL POTASSIUM CHANNEL MODULATORS | POSEIDON PHARMACEUTICALS A/S (DK) | 2005-01-13 | — | — | WO | disclosed |