Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241734 | 1.00 | POLB (0.49) | POLBMAPK1TSHRCYP2D6HIF1A | |
| SCHEMBL6240884 | 0.85 | POLB (0.49) | POLBMAPK1TSHRCYP2D6HIF1A | |
| SCHEMBL6239930 | 0.84 | TSHR (0.47) | POLBMAPK1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL6935238 | 0.84 | TSHR (0.47) | POLBMAPK1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL7224601 | 0.84 | TSHR (0.47) | POLBMAPK1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL11394616 | 0.84 | ALDH1A1 (0.46) | HPGDSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL29176910 | 0.84 | NLRP3 (0.46) | MAPK1SMN1; SMN2KDM4EPDCD1CD274 | |
| SCHEMBL11393576 | 0.84 | ALDH1A1 (0.46) | HPGDSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL6240614 | 0.83 | PPID (0.45) | POLBMAPK1TSHRCYP2D6HIF1A | |
| SCHEMBL7223415 | 0.82 | POLB (0.47) | POLBMAPK1TSHRCYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955046-B1 | Amino acid derivatives as anti-inflammatory agents | AJINOMOTO KK (JP) | 2005-06-22 | — | — | EP | claimed |
| EP-0955046-B1 | Amino acid derivatives as anti-inflammatory agents | AJINOMOTO KK (JP) | 2005-06-22 | — | — | EP | disclosed |
| US-6552061-B1 | For therapy and prophylaxis of inflammatory skin injuries or diseases | AJINOMOTO CO., INC. (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-0955046-A2 | Amino acid derivatives and anti-inflammatory agents | Ajinomoto Co., Inc. (JP) | 1999-11-10 | — | — | EP | disclosed |