Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.30 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18247712 | 0.77 | PKM (0.35) | PKMSSTR4HPSE | |
| SCHEMBL6232137 | 0.72 | F2R (0.32) | — | |
| SCHEMBL25187601 | 0.71 | DPP4 (0.39) | — | |
| SCHEMBL30369668 | 0.71 | DPP4 (0.39) | — | |
| SCHEMBL6238139 | 0.69 | ATM (0.40) | — | |
| SCHEMBL31298446 | 0.69 | ATM (0.40) | — | |
| SCHEMBL31298379 | 0.69 | ATM (0.40) | — | |
| SCHEMBL6235358 | 0.69 | ATM (0.40) | — | |
| SCHEMBL6232959 | 0.69 | ATM (0.40) | — | |
| SCHEMBL31481328 | 0.69 | HPSE (0.40) | PKMHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |