Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | AGXT | P21549 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237989 | 0.81 | IDO1 (0.49) | IDO1AGXTHTR1AADRA1DADRA1A | |
| SCHEMBL4914669 | 0.81 | CHRM2 (0.77) | CHRM2TAAR1CHRM1CHRM3SCN8A | |
| SCHEMBL4915334 | 0.81 | CHRM2 (0.77) | CHRM2TAAR1CHRM1CHRM3SCN8A | |
| SCHEMBL4913847 | 0.81 | CHRM2 (0.77) | CHRM2TAAR1CHRM1CHRM3SCN8A | |
| SCHEMBL5099393 | 0.81 | TAAR1 (0.68) | CHRM2TAAR1IDO1AGXTMAOB | |
| SCHEMBL4584077 | 0.80 | CHRM2 (0.77) | CHRM2TAAR1CHRM1CHRM3SCN8A | |
| SCHEMBL6240433 | 0.79 | CYP3A4 (0.51) | CHRM2TAAR1IDO1AGXTHTR1A | |
| SCHEMBL7547832 | 0.79 | CHRM2 (0.62) | CHRM2TAAR1IDO1AGXTHTR1A | |
| SCHEMBL10458644 | 0.79 | IDO1 (0.59) | CHRM2TAAR1IDO1AGXTHTR1A | |
| SCHEMBL28382952 | 0.78 | IDO1 (0.68) | CHRM2TAAR1IDO1AGXTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011697-A2 | SULFONAMIDE DERIVATIVES WITH ACTIVITY ON PROTEIN KINASE A AND B | ASTEX THERAPEUTICS LIMITED (GB) | 2005-02-10 | — | — | WO | disclosed |