Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 19/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2250760 | 0.82 | FYN (0.61) | FYNPIM1PIM2 | |
| SCHEMBL625256 | 0.81 | FYN (0.72) | FYNPIM1PIM2 | |
| SCHEMBL624903 | 0.76 | FYN (0.53) | FYNPIM1PIM2 | |
| SCHEMBL623808 | 0.75 | FYN (0.55) | FYNPIM1PIM2 | |
| SCHEMBL2250764 | 0.74 | FYN (0.81) | FYNPIM1PIM2 | |
| SCHEMBL625330 | 0.74 | PIM1 (0.52) | FYNPIM1PIM2 | |
| SCHEMBL30521786 | 0.73 | FYN (0.65) | FYN | |
| SCHEMBL30521733 | 0.73 | FYN (0.60) | FYN | |
| SCHEMBL20486035 | 0.73 | FYN (0.60) | FYN | |
| SCHEMBL1946034 | 0.73 | FYN (0.65) | FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |