Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 18/20 | 0.72 |
| ▸ | PIM1 | P11309 | 1/20 | 0.61 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.61 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2250764 | 0.93 | FYN (0.81) | FYNPIM1PIM2MKNK1 | |
| SCHEMBL1945953 | 0.89 | FYN (0.82) | FYNPIM1PIM2MKNK1 | |
| SCHEMBL1946515 | 0.84 | FYN (1.00) | FYNPIM1PIM2MKNK1 | |
| SCHEMBL1946037 | 0.83 | FYN (1.00) | FYNPIM1PIM2MKNK1 | |
| SCHEMBL625323 | 0.82 | MKNK1 (0.65) | FYNPIM1PIM2MKNK1 | |
| SCHEMBL1945870 | 0.82 | FYN (0.69) | FYNPIM1PIM2MKNK1 | |
| SCHEMBL623806 | 0.81 | FYN (0.54) | FYNPIM1PIM2 | |
| SCHEMBL625257 | 0.81 | FYN (0.47) | FYNPIM1PIM2 | |
| SCHEMBL1944935 | 0.80 | FYN (0.76) | FYN | |
| SCHEMBL1946859 | 0.79 | FYN (1.00) | FYNMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |