SCHEMBL6238224

SCHEMBL6238224

O=Cc1ccccc1OC(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.61
LMNA P02545 3/20 0.59
KMT2A Q03164 3/20 0.59
GAA P10253 1/20 0.59
ALDH1A1 P00352 5/20 0.57
HTT P42858 2/20 0.57
HPGD P15428 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
SRC P12931 2/20 0.55
MEN1 O00255 2/20 0.50
THRB P10828 1/20 0.50
BLM P54132 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
TRIM24 O15164 1/20 0.46
TRIM33 Q9UPN9 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TLR2 O60603 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29445574 1.00 PTGDR2 (0.61) PTGDR2LMNAKMT2AGAAALDH1A1
SCHEMBL9242543 0.87 HTT (0.50) PTGDR2LMNAKMT2AGAAALDH1A1
SCHEMBL8902287 0.87 HTT (0.50) PTGDR2LMNAKMT2AGAAALDH1A1
SCHEMBL1006065 0.84 ALDH1A1 (0.59) PTGDR2LMNAKMT2AGAAALDH1A1
SCHEMBL8579998 0.84 ALDH1A1 (0.59) PTGDR2LMNAKMT2AGAAALDH1A1
SCHEMBL2791739 0.83 PTGDR2 (0.44) PTGDR2LMNAKMT2AGAAALDH1A1
Benzene SCHEMBL3155472 0.83 ALDH1A1 (0.58) PTGDR2LMNAKMT2AGAAALDH1A1
SCHEMBL11199182 0.83 PTGDR2 (0.58) PTGDR2LMNAKMT2AGAAALDH1A1
SCHEMBL6374160 0.82 KMT2A (0.61) PTGDR2LMNAKMT2AGAAALDH1A1
SCHEMBL18196756 0.81 CA1 (0.59) PTGDR2LMNAKMT2AGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0433655-B1 2-(1-substituted-2-imidazolin-2-yl)benzoic and nicotinic acids and a method for their preparation AMERICAN CYANAMID CO (US) 1995-01-18 EP claimed
US-3952132-A ALKALI METAL SALT OF A PHENOL RESIN FUJI PHOTO FILM CO., LTD. (JA) 1976-04-20 US claimed
JP-3161439-A None JP disclosed
EP-1883645-B1 DERIVATIVES OF 4-OR 5-AMINOSALICYLIC ACID ANTIBE THERAPEUTICS INC (CA) 2011-06-29 EP disclosed
EP-1549682-B1 POLYMERS CONTAINING SILANE WACKER POLYMER SYSTEMS GMBH (DE) 2005-12-07 EP disclosed
EP-1549682-A1 POLYMERS CONTAINING SILANE Wacker Polymer Systems GmbH & Co. KG (DE) 2005-07-06 EP disclosed
WO-2004013187-A1 POLYMERS CONTAINING SILANE WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) 2004-02-12 WO disclosed
JP-H03161439-A NOVEL ANTIALLERGIC COMPOUND SHIKOKU CHEM CORP 1991-07-11 JP disclosed
US-4337280-A Desensitizer composition FUJI PHOTO FILM CO., LTD. (JP) 1982-06-29 US disclosed
US-4172727-A WHICH REDUCE OR EXTINGUISH CAPABILITY OF DEVELOPERS TO COLOR COLORLESS COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 1979-10-30 US disclosed
US-4147830-A Recording sheet FUJI PHOTO FILM CO., LTD. (JP) 1979-04-03 US disclosed
US-4078493-A Desensitizing using dry reverse lithographic plate FUJI PHOTO FILM CO., LTD. (JA) 1978-03-14 US disclosed
US-3952132-A ALKALI METAL SALT OF A PHENOL RESIN FUJI PHOTO FILM CO., LTD. (JA) 1976-04-20 US disclosed