SCHEMBL1006065

SCHEMBL1006065

O=Cc1ccccc1OC(=O)Oc1ccccc1C=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
HPGD P15428 2/20 0.59
HTT P42858 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
PTGDR2 Q9Y5Y4 1/20 0.58
SRC P12931 2/20 0.57
LMNA P02545 3/20 0.55
KMT2A Q03164 3/20 0.55
GAA P10253 1/20 0.55
MEN1 O00255 2/20 0.52
THRB P10828 1/20 0.52
BLM P54132 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
TRIM24 O15164 1/20 0.48
TRIM33 Q9UPN9 1/20 0.48
NPSR1 Q6W5P4 1/20 0.47
TLR2 O60603 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28101059 0.90 KMT2A (0.61) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL1665178 0.88 HPGD (0.58) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL8579998 0.86 ALDH1A1 (0.59) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL6238224 0.84 PTGDR2 (0.61) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL29445574 0.84 PTGDR2 (0.61) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL1665175 0.83 PTGDR2 (0.51) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL1667797 0.83 ALDH1A1 (0.52) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL1665945 0.83 PTGDR2 (0.47) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL1913791 0.83 PTGDR2 (0.47) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL13799146 0.83 SLC6A3 (0.58) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7666977-B2 Poly(carbonate-co-urea) copolymers and melt transesterification method of preparing these copolymers SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-02-23 US claimed
EP-2032628-A2 POLY(ARYLENE ETHER) BLOCK COPOLYMER COMPOSITIONS, METHODS, AND ARTICLES Sabic Innovative Plastics IP B.V. (NL) 2009-03-11 EP claimed
WO-2008136841-A1 POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-11-13 WO claimed
US-20080275209-A1 POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2008-11-06 US claimed
US-20080275185-A1 POLY(ARYLENE ETHER) BLOCK COPOLYMER COMPOSITIONS, METHODS, AND ARTICLES GENERAL ELECTRIC COMPANY (US) 2008-11-06 US claimed
WO-2007106296-A2 POLY(ARYLENE ETHER) BLOCK COPOLYMER COMPOSITIONS, METHODS, AND ARTICLES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2007-09-20 WO claimed
US-20070208145-A1 POLY(ARYLENE ETHER) BLOCK COPOLYMER COMPOSITIONS, METHODS, AND ARTICLES GENERAL ELECTRIC COMPANY (US) 2007-09-06 US claimed
US-20070208144-A1 POLY(ARYLENE ETHER) BLOCK COPOLYMER COMPOSITIONS, METHODS, AND ARTICLES GENERAL ELECTRIC COMPANY (US) 2007-09-06 US claimed
EP-4621010-A1 IMPACT PERFORMANCE MODIFIED MELT POLYCARBONATE SABIC Global Technologies B.V. (NL) 2025-09-24 EP disclosed
EP-3420031-B1 ARTICLES OF MANUFACTURE USING AN IMPACT PERFORMANCE MODIFIED MELT POLYCARBONATE SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-04-30 EP disclosed
EP-3420030-B1 IMPACT PERFORMANCE MODIFIED MELT POLYCARBONATE SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-04-30 EP disclosed
CN-114854000-B Bio-based polycarbonate copolymer and preparation method thereof 华东理工大学 2024-02-02 CN disclosed
CN-108884307-B Articles of manufacture using impact modified melt polycarbonates 沙特基础工业全球技术公司 2023-11-21 CN disclosed
CN-108779323-B Melt polycarbonate with improved impact properties 沙特基础工业全球技术公司 2023-11-21 CN disclosed
WO-2005073273-A1 PROCESS FOR THE PRODUCTION OF COPOLYCARBONATES WITH REDUCED COLOR GENERAL ELECTRIC COMPANY (US) 2005-08-11 WO disclosed
WO-2005073274-A1 PROCESS FOR PRODUCTION OF COPOLYCARBONATES WITH REDUCED COLOR GENERAL ELECTRIC COMPANY (US) 2005-08-11 WO disclosed
US-20050171323-A1 Process for the production of copolycarbonates with reduced color GENERAL ELECTRIC COMPANY (US) 2005-08-04 US disclosed
US-20050171322-A1 Process for the production of copolycarbonates with reduced color SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2005-08-04 US disclosed
WO-2005066239-A1 ALIPHATIC DIOL POLYCARBONATES AND THEIR PREPARATION GENERAL ELECTRIC COMPANY (US) 2005-07-21 WO disclosed
US-20050143554-A1 ALIPHATIC DIOL POLYCARBONATES AND THEIR PREPARATION GENERAL ELECTRIC COMPANY 2005-06-30 US disclosed