Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.78 |
| ▸ | RAB9A | P51151 | 4/20 | 0.78 |
| ▸ | CASP1 | P29466 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22441355 | 0.89 | RAB9A (0.91) | NPC1RAB9ACASP1TSHRSMN1; SMN2 | |
| SCHEMBL14155719 | 0.84 | RAB9A (0.83) | NPC1RAB9ACASP1TSHRSMN1; SMN2 | |
| SCHEMBL10943133 | 0.80 | RAB9A (0.86) | NPC1RAB9ACASP1TSHRSMN1; SMN2 | |
| SCHEMBL12971158 | 0.79 | RAB9A (0.64) | NPC1RAB9ACASP1TSHRSMN1; SMN2 | |
| SCHEMBL5636399 | 0.78 | RAB9A (0.72) | NPC1RAB9ACASP1TSHRSMN1; SMN2 | |
| SCHEMBL12411578 | 0.77 | RAB9A (0.69) | NPC1RAB9ACASP1TSHRSMN1; SMN2 | |
| SCHEMBL7564852 | 0.76 | RAB9A (0.79) | NPC1RAB9ACASP1TSHRSMN1; SMN2 | |
| SCHEMBL22441244 | 0.76 | RAB9A (0.69) | NPC1RAB9ACASP1TSHRSMN1; SMN2 | |
| SCHEMBL28735058 | 0.75 | NPC1 (0.68) | NPC1RAB9ACASP1TSHRSMN1; SMN2 | |
| SCHEMBL29893174 | 0.75 | RAB9A (0.76) | NPC1RAB9ACASP1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005010011-A2 | METHODS OF SYNTHESIS OF ACYLOXYALKYL COMPOUNDS | XENOPORT, INC. (US) | 2005-02-03 | — | — | WO | disclosed |