SCHEMBL7564852

SCHEMBL7564852

CCCCOC(=O)Nc1ccc(NC(=O)OCCCC)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 10/20 0.79
SMN1; SMN2 Q16637 10/20 0.79
NPC1 O15118 9/20 0.79
HPGD P15428 7/20 0.79
MAPT P10636 4/20 0.79
ALDH1A1 P00352 4/20 0.79
MAPK1 P28482 2/20 0.79
KDM4E B2RXH2 2/20 0.79
CASP1 P29466 1/20 0.79
MCL1 Q07820 1/20 0.79
L3MBTL1 Q9Y468 1/20 0.79
KMT2A Q03164 3/20 0.68
TP53 P04637 1/20 0.68
NFKB1 P19838 1/20 0.68
NFKB2 Q00653 1/20 0.68
RELA Q04206 1/20 0.68
CYP1A2 P05177 3/20 0.68
CYP2C19 P33261 3/20 0.68
CYP2C9 P11712 2/20 0.68
LMNA P02545 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13387589 0.95 RAB9A (0.72) RAB9ASMN1; SMN2NPC1HPGDMAPT
SCHEMBL10192215 0.93 RAB9A (0.70) RAB9ASMN1; SMN2NPC1HPGDMAPT
SCHEMBL1699197 0.93 SMN1; SMN2 (0.70) RAB9ASMN1; SMN2NPC1HPGDMAPT
SCHEMBL7564856 0.93 RAB9A (0.70) RAB9ASMN1; SMN2NPC1HPGDMAPT
SCHEMBL12411578 0.93 RAB9A (0.69) RAB9ASMN1; SMN2NPC1HPGDMAPT
SCHEMBL1690744 0.92 FAAH (0.69) RAB9ASMN1; SMN2NPC1HPGDMAPT
SCHEMBL21059160 0.92 RAB9A (0.68) RAB9ASMN1; SMN2NPC1HPGDMAPT
SCHEMBL21059157 0.92 RAB9A (0.73) RAB9ASMN1; SMN2NPC1HPGDMAPT
SCHEMBL21059190 0.92 RAB9A (0.73) RAB9ASMN1; SMN2NPC1HPGDMAPT
SCHEMBL1022959 0.92 RAB9A (0.68) RAB9ASMN1; SMN2NPC1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9000219-B2 Method for treatment of isocyanate residue, and method for treatment of carbonate MITSUI CHEMICALS, INC. (JP) 2015-04-07 US disclosed
US-20120271067-A1 METHOD FOR TREATMENT OF ISOCYANATE RESIDUE, AND METHOD FOR TREATMENT OF CARBONATE MITSUI CHEMICALS, INC. 2012-10-25 US disclosed
EP-0855393-B1 BISBENZOTRIAZOLYLPHENOLS OTSUKA KAGAKU KK (JP) 2002-08-14 EP disclosed
US-5922882-A ULTRAVIOLET RADIATION ABSORBER; COPOLYMERIZATION COMPONENT OF BISBENZOTRIAZOLE COMPRISING A COPOLYCARBONATE, A COPOLYESTER, A COPOLYURETHANE AND A COPOLYURETHANEURA OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1999-07-13 US disclosed
EP-0855393-A1 BISBENZOTRIAZOLYLPHENOLS OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1998-07-29 EP disclosed
US-4499167-A Photoconductive compositions comprising an organic photoconductor and an amide compound and electro-photographic light-sensitive materials using the compositions FUJI PHOTO FILM CO., LTD. (JP) 1985-02-12 US disclosed
US-4018744-A Storage stable polyester-polyurethane-producing compositions ATLANTIC RICHFIELD COMPANY (US) 1977-04-19 US disclosed
US-3950285-A PREPARATION OF POLYMERIC URETHANES FROM DICARBAMATES ATLANTIC RICHFIELD COMPANY (US) 1976-04-13 US disclosed