Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236118 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4604208 | 0.74 | KMT2A (0.48) | ALDH1A1POLBTSHRKMT2AHTR2A | |
| SCHEMBL2091553 | 0.74 | ALDH1A1 (0.46) | ALDH1A1POLBTSHRKMT2ACYP1A2 | |
| SCHEMBL3729996 | 0.70 | ALDH1A1 (0.73) | ALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL25113519 | 0.69 | GFER (0.39) | ALDH1A1POLBTSHRKMT2AGRM2 | |
| SCHEMBL29924261 | 0.68 | MAPT (0.53) | ALDH1A1POLBTSHRKMT2AHTR2A | |
| SCHEMBL29149941 | 0.68 | MAPT (0.53) | ALDH1A1POLBTSHRKMT2AHTR2A | |
| SCHEMBL25113521 | 0.68 | PTGER1 (0.38) | ALDH1A1POLBTSHRKMT2ACYP1A2 | |
| SCHEMBL17664016 | 0.68 | KMT2A (0.56) | ALDH1A1POLBTSHRKMT2AHTR2A | |
| SCHEMBL2094893 | 0.67 | ALDH1A1 (0.50) | ALDH1A1POLBTSHRSLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | claimed |
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |