Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30714076 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL14632631 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL29172894 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL19643017 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL16713412 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL25409488 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL10596725 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL3630331 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL14632707 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL14782443 | 0.97 | TSHR (0.63) | TSHRLMNANFKB1PMP22PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4642221-A | AROMATIC TRIAZOLES AND IMINODICARBOXYLIC ACID DERIVATIVES | ATLANTIC RICHFIELD COMPANY (US) | 1987-02-10 | — | — | US | claimed |
| EP-1124881-B1 | CONTINUOUS POLYMERIZATION PROCESS FOR PREPARING POLYAMIDES FROM OMEGA-AMINONITRILES | INVISTA TECH SARL (US) | 2005-04-27 | — | — | EP | disclosed |
| US-6815527-B2 | REACTING AMINONITRILE WITH WATER IN ORGANIC LIQUID DILUENT AT ELEVATED TEMPERATURE AND PRESSURE IN FLOW TUBE WITH SELECTED BRONSTED ACID CATALYST, FURTHER REACTING TO FORM AND SEPARATE GAS PHASE, MIXING REMAINDER WITH WATER TO FORM PRODUCT | BASF AKTIENGESELLSCHAFT (DE) | 2004-11-09 | — | — | US | disclosed |
| US-20040102604-A1 | Continuous method fore producing polyamides from aminonitriles | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-27 | — | — | US | disclosed |
| US-6660857-B2 | Reuse of carpet wastes | DSM N.V. (NL) | 2003-12-09 | — | — | US | disclosed |
| EP-1257532-B1 | PROCESS FOR THE PREPARATION OF $g(e)-CAPROLACTAM | DSM IP ASSETS BV (NL) | 2003-09-10 | — | — | EP | disclosed |
| EP-1335897-A1 | PRODUCTION OF 6-AMINOCAPROIC ACID | INVISTA Technologies S.à.r.l. (US) | 2003-08-20 | — | — | EP | disclosed |
| US-20030065169-A1 | Process for the preparation of epsilon-caprolactam | DSM N.V. | 2003-04-03 | — | — | US | disclosed |
| EP-1257532-A1 | PROCESS FOR THE PREPARATION OF $g(e)-CAPROLACTAM | DSM N.V. (NL) | 2002-11-20 | — | — | EP | disclosed |
| WO-2002040440-A1 | PRODUCTION OF 6-AMINOCAPROIC ACID | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-05-23 | — | — | WO | disclosed |
| US-6372939-B1 | HYDROFORMYLATING 3-PENTENENITRILE IN PRESENCE OF CATALYST COMPRISING GROUP VIII ELEMENT TO PRODUCE MIXTURE OF FORMYLVALERONITRILES, OXIDIZING TO CYANOVALERIC ACIDS, CATALYTICALLY HYDROGENATING TO 6-AMINOCAPROIC ACID AND ISOMERS | E.I. DU PONT DE NEMOURS AND COMPANY | 2002-04-16 | — | — | US | disclosed |
| EP-1124881-A1 | CONTINUOUS POLYMERIZATION PROCESS FOR PREPARING POLYAMIDES FROM OMEGA-AMINONITRILES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2001056984-A1 | PROCESS FOR THE PREPARATION OF ε-CAPROLACTAM | DSM N.V. (NL) | 2001-08-09 | — | — | WO | disclosed |
| EP-1122241-A1 | Process for the preparation of epsilon-caprolactam | DSM N.V. (NL) | 2001-08-08 | — | — | EP | disclosed |
| US-6201096-B1 | SUCH AS 6-AMINOCAPRONITRILE, WHICH IS INTRODUCED AT THE TOP OF A VERTICAL MULTISTAGE REACTOR BEING SWEPT COUNTERCURRENTLY WITH STEAM AND POLYAMIDE SUCH AS NYLON 6 IS RECOVERED NEAR THE BOTTOM OF THE REACTOR; LOW UNREACTED NITRILE END GROUPS | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-03-13 | — | — | US | disclosed |
| WO-2000024808-A1 | CONTINUOUS POLYMERIZATION PROCESS FOR PREPARING POLYAMIDES FROM OMEGA-AMINONITRILES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-04 | — | — | WO | disclosed |
| EP-0918547-A2 | RADIOLABELED ANNEXINS | NEORX CORPORATION (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004294-A2 | RADIOLABELED ANNEXINS | NEORX CORPORATION (US) | 1998-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065169-A1 | Process for the preparation of epsilon-caprolactam | MCCC2, ACMSD, PCCA | TSHR 445/4885LMNA 1667/4885NFKB1 1521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.