SCHEMBL6238908

SCHEMBL6238908

c1ccc(-c2sc(-c3ccccc3)c3ccccc23)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
MAPT P10636 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C19 P33261 2/20 0.41
GPR3 P46089 1/20 0.41
ALOX5 P09917 1/20 0.40
TDO2 P48775 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
GAA P10253 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
MAPK1 P28482 2/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
GRM6 O15303 1/20 0.35
HTT P42858 1/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14190040 0.97 ALDH1A1 (0.42) ALDH1A1MAPTCYP1A2CYP2D6CYP2C19
SCHEMBL23596749 0.86 ALDH1A1 (0.43) ALDH1A1MAPTCYP1A2CYP2D6CYP2C19
SCHEMBL23597104 0.84 L3MBTL1 (0.38) ALDH1A1MAPTCYP1A2CYP2D6CYP2C19
SCHEMBL23596347 0.82 ALDH1A1 (0.40) ALDH1A1L3MBTL1MAPK1
SCHEMBL23596172 0.82 ALDH1A1 (0.40) ALDH1A1L3MBTL1MAPK1
SCHEMBL23597284 0.81 L3MBTL1 (0.54) MAPTGPR3L3MBTL1RAB9AMEN1
SCHEMBL23596900 0.81 ALDH1A1 (0.35) ALDH1A1MAPTCYP1A2CYP2D6CYP2C19
SCHEMBL23596190 0.81 L3MBTL1 (0.36) ALDH1A1MAPTCYP1A2CYP2D6CYP2C19
SCHEMBL23596343 0.81 ENPP1 (0.41) ALDH1A1L3MBTL1MAPK1
SCHEMBL23596022 0.79 ALDH1A1 (0.46) ALDH1A1MAPTKDM4EMAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1072614-B1 Method for polymerizing vinyl monomers in a coated reactor SHINETSU CHEMICAL CO (JP) 2005-07-06 EP disclosed
EP-0934955-B1 Polymerization process characterized by a two layer coating against scale formation deposited using a steam carrier SHINETSU CHEMICAL CO (JP) 2003-04-16 EP disclosed
US-6362291-B1 PRETREATING VESSEL HAS ANTIDEPOSIT COATING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-03-26 US disclosed
US-6335403-B1 ANTISCALING AGENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-01-01 US disclosed
US-6320001-B1 COATING INNER WALL SURFACES WITH A POLYMER SCALE PREVENTIVE FILM OF AN AROMATIC OR HETEROCYCLIC COMPOUND HAVING 5 OR MORE CONJUGATED PI BONDS DYE AND/OR PIGMENT ON THE FIRST LAYER AND A SECOND LAYER OF A DYE AND/OR PIGMENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-11-20 US disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
EP-1072614-A1 Method for polymerizing vinyl monomers in a coated reactor SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-01-31 EP disclosed
EP-1063242-A1 Process for producing a polymer by polymerization of a monomer having an ethylenic double bond SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-12-27 EP disclosed
EP-1043338-A1 Polymerisation process in a reactor with double coating against scale formation SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-10-11 EP disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-6037426-A POLYMERIZING MONOMER HAVING ETHYLENIC DOUBLE BOND IN POLYMERIZATION VESSEL HAVING BILAYER POLYMER SCALE PREVENTIVE COATING FILM ON INNER WALL SURFACES SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-03-14 US disclosed
EP-0934955-A1 Polymerization process characterized by a two layer coating against scale formation deposited using a steam carrier SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-08-11 EP disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed