Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | AGXT | P21549 | 2/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | NOS3 | P29474 | 4/20 | 0.36 |
| ▸ | NOS1 | P29475 | 4/20 | 0.36 |
| ▸ | NOS2 | P35228 | 4/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236177 | 1.00 | IDO1 (0.40) | IDO1AGXTCARM1PRMT6SLC6A4 | |
| SCHEMBL6238619 | 0.85 | DPP4 (0.44) | NOS3NOS1NOS2 | |
| SCHEMBL24928599 | 0.85 | DPP4 (0.44) | NOS3NOS1NOS2 | |
| SCHEMBL16761713 | 0.76 | IDO1 (0.46) | IDO1AGXTCARM1PRMT6SLC6A4 | |
| SCHEMBL16762033 | 0.76 | IDO1 (0.46) | IDO1AGXTCARM1PRMT6SLC6A4 | |
| SCHEMBL16761712 | 0.76 | IDO1 (0.46) | IDO1AGXTCARM1PRMT6SLC6A4 | |
| SCHEMBL6239006 | 0.76 | EPHX2 (0.38) | IDO1AGXTCARM1PRMT6SLC6A4 | |
| SCHEMBL6236176 | 0.76 | EPHX2 (0.38) | IDO1AGXTCARM1PRMT6SLC6A4 | |
| SCHEMBL8177812 | 0.74 | GRIK1 (0.44) | — | |
| SCHEMBL3182056 | 0.74 | GRIK1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011697-A2 | SULFONAMIDE DERIVATIVES WITH ACTIVITY ON PROTEIN KINASE A AND B | ASTEX THERAPEUTICS LIMITED (GB) | 2005-02-10 | — | — | WO | disclosed |