Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1416500 | 0.89 | RECQL (0.62) | RECQLTSHRMAPK1GLAHPGD | |
| SCHEMBL1416644 | 0.89 | RECQL (0.62) | RECQLTSHRMAPK1GLAHPGD | |
| Cetylpyridinium SCHEMBL6816053 | 0.89 | RECQL (0.62) | RECQLTSHRMAPK1GLAHPGD | |
| Cetylpyridinium SCHEMBL31012333 | 0.87 | RECQL (0.63) | RECQLTSHRMAPK1GLAHPGD | |
| Hydrochloric Acid SCHEMBL20548536 | 0.87 | RECQL (0.63) | RECQLTSHRMAPK1GLAHPGD | |
| SCHEMBL1255772 | 0.86 | RECQL (0.66) | RECQLTSHRMAPK1GLAHPGD | |
| Benzene SCHEMBL15752865 | 0.85 | RECQL (0.88) | RECQLTSHRMAPK1GLAHPGD | |
| Octadecyl Sulfate SCHEMBL10845191 | 0.85 | RECQL (0.88) | RECQLTSHRMAPK1GLAHPGD | |
| Benzene SCHEMBL65602 | 0.85 | RECQL (0.88) | RECQLTSHRMAPK1GLAHPGD | |
| Benzene SCHEMBL4578661 | 0.85 | RECQL (0.81) | RECQLTSHRMAPK1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050279632-A1 | Electrophoresis process using ionic liquids | LARGE SCALE PROTEOMICS CORPORATION (US) | 2005-12-22 | — | — | US | claimed |
| EP-1536870-A2 | ELECTROPHORESIS PROCESS USING IONIC LIQUIDS | Large Scale Proteomics Corp. (US) | 2005-06-08 | — | — | EP | claimed |
| WO-2004024279-A9 | ELECTROPHORESIS PROCESS USING IONIC LIQUIDS | LARGE SCALE PROTEOMICS CORP (US) | 2004-06-03 | — | — | WO | claimed |
| WO-2004024279-A3 | ELECTROPHORESIS PROCESS USING IONIC LIQUIDS | LARGE SCALE PROTEOMICS CORP (US) | 2004-04-29 | — | — | WO | claimed |
| WO-2004024279-A2 | ELECTROPHORESIS PROCESS USING IONIC LIQUIDS | LARGE SCALE PROTEOMICS CORPORATION (US) | 2004-03-25 | — | — | WO | claimed |
| US-20040031685-A1 | Electrophoresis process using ionic liquids | LARGE SCALE PROTEMICS CORP. | 2004-02-19 | — | — | US | claimed |
| US-20050279632-A1 | Electrophoresis process using ionic liquids | LARGE SCALE PROTEOMICS CORPORATION (US) | 2005-12-22 | — | — | US | disclosed |
| US-6939453-B2 | Electrophoresis process using ionic liquids | LARGE SCALE PROTEOMICS CORPORATION (US) | 2005-09-06 | — | — | US | disclosed |
| EP-1536870-A2 | ELECTROPHORESIS PROCESS USING IONIC LIQUIDS | Large Scale Proteomics Corp. (US) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004024279-A9 | ELECTROPHORESIS PROCESS USING IONIC LIQUIDS | LARGE SCALE PROTEOMICS CORP (US) | 2004-06-03 | — | — | WO | disclosed |
| WO-2004024279-A3 | ELECTROPHORESIS PROCESS USING IONIC LIQUIDS | LARGE SCALE PROTEOMICS CORP (US) | 2004-04-29 | — | — | WO | disclosed |
| WO-2004024279-A2 | ELECTROPHORESIS PROCESS USING IONIC LIQUIDS | LARGE SCALE PROTEOMICS CORPORATION (US) | 2004-03-25 | — | — | WO | disclosed |
| US-20040031685-A1 | Electrophoresis process using ionic liquids | LARGE SCALE PROTEMICS CORP. | 2004-02-19 | — | — | US | disclosed |