Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | DRD4 | P21917 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243257 | 0.93 | ALDH1A1 (0.43) | KDM4ELMNADRD4MAPTALDH1A1 | |
| SCHEMBL9031046 | 0.71 | DRD4 (0.60) | KDM4ELMNADRD4MAPTALDH1A1 | |
| SCHEMBL4001565 | 0.71 | KDM4E (0.63) | KDM4ELMNADRD4MAPTALDH1A1 | |
| SCHEMBL6243264 | 0.70 | KMT2A (0.47) | KDM4ELMNAMAPTALDH1A1POLB | |
| SCHEMBL4005740 | 0.69 | KDM4E (0.60) | KDM4ELMNADRD4MAPTALDH1A1 | |
| SCHEMBL6275271 | 0.67 | KDM4E (0.74) | KDM4ELMNADRD4MAPTALDH1A1 | |
| SCHEMBL10682138 | 0.67 | DRD4 (0.52) | KDM4ELMNADRD4MAPTALDH1A1 | |
| SCHEMBL9808189 | 0.66 | DRD4 (0.52) | KDM4ELMNADRD4MAPTALDH1A1 | |
| SCHEMBL6240166 | 0.66 | LMNA (0.51) | KDM4ELMNADRD4MAPTALDH1A1 | |
| SCHEMBL2327539 | 0.65 | ALDH1A1 (0.64) | KDM4ELMNADRD4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | disclosed |