Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1740099 | 0.88 | ALDH1A1 (0.46) | ALDH1A1PTPN1BLMLMNATSHR | |
| SCHEMBL1739665 | 0.88 | ALDH1A1 (0.50) | ALDH1A1LMNATSHRCYP3A4ATM | |
| SCHEMBL29184097 | 0.87 | LMNA (0.42) | ALDH1A1PTPN1BLMLMNATSHR | |
| SCHEMBL28429440 | 0.87 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRCYP3A4ATM | |
| SCHEMBL1740945 | 0.86 | ALDH1A1 (0.46) | ALDH1A1PTPN1BLMLMNATSHR | |
| SCHEMBL1739669 | 0.85 | LMNA (0.52) | ALDH1A1LMNATSHRCYP3A4ATM | |
| SCHEMBL29517193 | 0.81 | LMNA (0.46) | ALDH1A1LMNATSHRCYP3A4ATM | |
| SCHEMBL27434544 | 0.81 | LMNA (0.46) | ALDH1A1LMNATSHRCYP3A4ATM | |
| SCHEMBL1740948 | 0.81 | LMNA (0.55) | ALDH1A1LMNATSHRCYP3A4ATM | |
| SCHEMBL1740100 | 0.80 | LMNA (0.55) | ALDH1A1LMNATSHRCYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549669-A1 | TUMOR TARGETING AGENTS AND USES THEREOF | Karyon OY (FI) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004031221-A1 | TUMOR TARGETING AGENTS AND USES THEREOF | KARYON OY (FI) | 2004-04-15 | — | — | WO | disclosed |