Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.74 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.74 |
| ▸ | TUBB | P07437 | 5/20 | 0.74 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.74 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.74 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.74 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.74 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.74 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.74 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.74 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.74 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.74 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.74 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.74 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.74 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.74 |
| ▸ | TUBB8B | A6NNZ2 | 2/20 | 0.74 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15658846 | 0.86 | CYP3A4 (0.74) | CYP3A4TUBB4ATUBBTUBB4BTUBB3 | |
| SCHEMBL15658844 | 0.86 | CYP3A4 (0.74) | CYP3A4TUBB4ATUBBTUBB4BTUBB3 | |
| Noscapine SCHEMBL4559 | 0.86 | CYP3A4 (1.00) | CYP3A4TUBB4ATUBBTUBB4BTUBB3 | |
| Noscapine SCHEMBL29365828 | 0.86 | CYP3A4 (1.00) | CYP3A4TUBB4ATUBBTUBB4BTUBB3 | |
| Noscapine SCHEMBL7862895 | 0.86 | CYP3A4 (1.00) | CYP3A4TUBB4ATUBBTUBB4BTUBB3 | |
| Noscapine SCHEMBL10307295 | 0.86 | CYP3A4 (1.00) | CYP3A4TUBB4ATUBBTUBB4BTUBB3 | |
| Noscapine SCHEMBL2494164 | 0.86 | CYP3A4 (1.00) | CYP3A4TUBB4ATUBBTUBB4BTUBB3 | |
| Noscapine SCHEMBL14400084 | 0.86 | CYP3A4 (1.00) | CYP3A4TUBB4ATUBBTUBB4BTUBB3 | |
| Noscapine SCHEMBL12481369 | 0.86 | CYP3A4 (1.00) | CYP3A4TUBB4ATUBBTUBB4BTUBB3 | |
| Noscapine SCHEMBL14386820 | 0.86 | CYP3A4 (1.00) | CYP3A4TUBB4ATUBBTUBB4BTUBB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005020911-A2 | BENZO[1, 3]DIOXOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND PROCESSES OF MAKING AND USING THE SAME | ATHERSYS, INC. (US) | 2005-03-10 | — | — | WO | disclosed |
| US-20050049278-A1 | Benzo[1,3]dioxole compounds, pharmaceutical compositions thereof, and processes of making and using the same | ATHERSYS, INC. | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049278-A1 | Benzo[1,3]dioxole compounds, pharmaceutical compositions thereof, and processes of making and using the same | CYP4X1, BBOX1, CYP1B1 | CYP3A4 45/4885TUBB4A 3893/4885TUBB 4336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.