Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2995101 | 0.84 | HDAC1 (0.46) | PTGER1PTGER4PTGER3PTGER2HDAC1 | |
| SCHEMBL6239378 | 0.80 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DPTGER1 | |
| SCHEMBL6238928 | 0.72 | BCHE (0.42) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9823156 | 0.72 | HDAC1 (0.54) | HDAC1HDAC3HDAC2NCOR2LPAR1 | |
| SCHEMBL1798552 | 0.71 | HDAC1 (0.41) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL27657930 | 0.71 | HDAC3 (0.52) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL1800074 | 0.70 | HDAC1 (0.42) | HDAC1HDAC3HDAC2NCOR2LPAR1 | |
| SCHEMBL3108959 | 0.70 | NR1H4 (0.45) | HDAC1HDAC3HDAC2NCOR2RARB | |
| SCHEMBL1801270 | 0.70 | HDAC1 (0.43) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL16468251 | 0.70 | HDAC1 (0.43) | HDAC1HDAC3HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216225-B1 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | BAYER HEALTHCARE AG (DE) | 2005-07-06 | — | — | EP | disclosed |