Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2995581 | 0.87 | ALDH1A1 (0.38) | PTGER1PTGER4PTGER3PTGER2LTA4H | |
| SCHEMBL6238928 | 0.80 | BCHE (0.42) | PDE4APDE4BPDE4CPDE4DLTA4H | |
| SCHEMBL6239166 | 0.80 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DRARB | |
| SCHEMBL13009690 | 0.75 | ALDH1A1 (0.42) | PTGER1PTGER4PTGER3PTGER2LTA4H | |
| SCHEMBL13009685 | 0.73 | ALOX5 (0.46) | PTGER1PTGER4PTGER3PTGER2LTA4H | |
| SCHEMBL6240043 | 0.72 | PTGER1 (0.40) | PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL13009683 | 0.72 | ALOX5 (0.43) | LTA4H | |
| SCHEMBL6241365 | 0.71 | SLC1A5 (0.41) | PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL6242841 | 0.70 | CYP4F2 (0.44) | LTA4H | |
| SCHEMBL13009688 | 0.69 | PTGER1 (0.43) | PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216225-B1 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | BAYER HEALTHCARE AG (DE) | 2005-07-06 | — | — | EP | disclosed |