SCHEMBL7559627

SCHEMBL7559627

CCCCCCCCC(F)([C](F)F)[Si](OC)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.39
LPAR1 Q92633 1/20 0.39
LPAR3 Q9UBY5 1/20 0.39
FAAH O00519 7/20 0.33
CES1 P23141 6/20 0.33
SMPD1 P17405 3/20 0.33
GGPS1 O95749 2/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
FDPS P14324 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6512512 1.00 CES2 (0.39) CES2LPAR1LPAR3FAAHCES1
SCHEMBL29012028 0.76 CES2 (0.39) CES2LPAR1LPAR3FAAHCES1
SCHEMBL3440984 0.76 CES2 (0.39) CES2LPAR1LPAR3FAAHCES1
SCHEMBL6239174 0.76 CES2 (0.39) CES2LPAR1LPAR3FAAHCES1
SCHEMBL28251609 0.71 TSHR (0.38) CES2LPAR1LPAR3SMPD1GGPS1
SCHEMBL3913347 0.70 CES2 (0.43) CES2SMPD1GGPS1FDPS
SCHEMBL3912723 0.70 CES2 (0.43) CES2SMPD1GGPS1FDPS
SCHEMBL3920576 0.70 CES2 (0.43) CES2SMPD1GGPS1FDPS
SCHEMBL2927935 0.70 TSHR (0.36) CES2LPAR1LPAR3SMPD1GGPS1
SCHEMBL8845866 0.70 TSHR (0.36) CES2LPAR1LPAR3SMPD1GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020192385-A1 Method of applying a fluoroalkyl-functional organopolysiloxane coationg having durable water and oil repellent properties to polymeric substrates DEGUSSA AG (DE) 2002-12-19 US disclosed
US-20020084553-A1 Process for molding hydrophobic polymers to produce surfaces with stable water- and oil-repellent properties CREAVIS GESELLSCHAFT FUER TECHN. UND INNOV. MBH (DE) 2002-07-04 US disclosed