SCHEMBL6239230

SCHEMBL6239230

CCC1=C([Si](C)(C)C2=C(CC)[CH]c3cccc(C)c32)c2c(C)cccc2[CH]1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HEXA P06865 1/20 0.33
HEXB P07686 1/20 0.33
CD44 P16070 1/20 0.31
REN P00797 1/20 0.31
TLR8 Q9NR97 1/20 0.31
SRC P12931 1/20 0.30
NOS3 P29474 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3154185 0.78 ELANE (0.33) CD44SRC
SCHEMBL6234174 0.78 HEXA (0.36) HEXAHEXB
SCHEMBL7593795 0.75 TAAR1 (0.31)
SCHEMBL6240155 0.73 SETD7 (0.30)
SCHEMBL7006274 0.71 HDAC4 (0.38)
SCHEMBL6234188 0.69 ELANE (0.37)
SCHEMBL216416 0.68 TSHR (0.31) NOS2
SCHEMBL2050326 0.68 CD44 (0.48) CD44SRCNOS3NOS2
SCHEMBL6650697 0.64 NPC1 (0.38)
SCHEMBL5691590 0.61 PDCD1 (0.39) HEXAHEXB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6143686-A FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER EXXON CHEMICAL PATENTS, INC. (US) 2000-11-07 US claimed
WO-2005003184-A1 POLYMERIZATION PROCESSES USING ANTISTATIC AGENTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-01-13 WO disclosed
EP-1373337-A2 PROPYLENE POLYMERS FOR FILMS Exxonmobil Chemical Patents Inc. (US) 2004-01-02 EP disclosed
EP-1311593-A2 POLYPROPYLENE FILMS Exxonmobil Chemical Patents Inc. (US) 2003-05-21 EP disclosed
EP-1263909-A2 POLYPROPYLENE-BASED ADHESIVE COMPOSITIONS ExxonMobil Chemical Patents Inc. (US) 2002-12-11 EP disclosed
WO-2002070572-A2 PROPYLENE POLYMERS FOR FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-09-12 WO disclosed
WO-2002070570-A2 PROPYLENE POLYMERS FOR FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-09-12 WO disclosed
US-20020052446-A1 Composition based on monofluorometal complexes BAYER AKTIENGESELLSCHAFT (DE) 2002-05-02 US disclosed
WO-2002016480-A2 POLYPROPYLENE FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-02-28 WO disclosed
WO-2001046277-A2 POLYPROPYLENE-BASED ADHESIVE COMPOSITIONS EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2001-06-28 WO disclosed
US-6143686-A FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER EXXON CHEMICAL PATENTS, INC. (US) 2000-11-07 US disclosed