SCHEMBL3154185

SCHEMBL3154185

CC1=C([Si](C)(C)C2=C(C)[CH]c3cccc(C)c32)c2c(C)cccc2[CH]1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA7 P43166 2/20 0.32
CA9 Q16790 2/20 0.32
CD44 P16070 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
SRC P12931 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
PARP1 P09874 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6650697 0.84 NPC1 (0.38) ELANECA1CA2CA7CA9
SCHEMBL6723398 0.78 CA2 (0.35) ELANECA2ALDH1A1
SCHEMBL6234188 0.78 ELANE (0.37) ELANE
SCHEMBL4453364 0.77 ADORA3 (0.36) ALDH1A1
SCHEMBL218448 0.74 CYP2A6 (0.36) CA1CA2CA7CA9CD44
SCHEMBL2050326 0.73 CD44 (0.48) CA1CA2CA7CA9CD44
SCHEMBL7108778 0.71 NQO1 (0.31)
SCHEMBL3154760 0.71 CES1 (0.41) ELANECYP1A2CYP2A6ALDH1A1
SCHEMBL6234916 0.70 HDAC4 (0.43) CYP1A2ALDH1A1
SCHEMBL3147081 0.70 BRD4 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6143686-A FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER EXXON CHEMICAL PATENTS, INC. (US) 2000-11-07 US claimed
EP-1270614-B1 Copolymers containing propylene and alpha-olefin comonomer BASELL POLYOLEFINE GMBH (DE) 2010-01-27 EP disclosed
WO-2005003184-A1 POLYMERIZATION PROCESSES USING ANTISTATIC AGENTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-01-13 WO disclosed
EP-1315858-A1 POLYPROPYLENE FIBERS AND FABRICS Exxonmobil Chemical Patents Inc. (US) 2003-06-04 EP disclosed
EP-1313782-A1 POLYPROPYLENE POLYMERS Exxonmobil Chemical Patents Inc. (US) 2003-05-28 EP disclosed
EP-1311593-A2 POLYPROPYLENE FILMS Exxonmobil Chemical Patents Inc. (US) 2003-05-21 EP disclosed
EP-0889059-B1 Catalyst based on monoazadiene metal complexes BAYER AG (DE) 2003-02-12 EP disclosed
EP-1263909-A2 POLYPROPYLENE-BASED ADHESIVE COMPOSITIONS ExxonMobil Chemical Patents Inc. (US) 2002-12-11 EP disclosed
WO-2002070570-A2 PROPYLENE POLYMERS FOR FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-09-12 WO disclosed
EP-1237995-A1 FOAMABLE POLYPROPYLENE POLYMERS AND THEIR USE ExxonMobil Chemical Patents Inc. (US) 2002-09-11 EP disclosed
US-20020052446-A1 Composition based on monofluorometal complexes BAYER AKTIENGESELLSCHAFT (DE) 2002-05-02 US disclosed
WO-2002016480-A2 POLYPROPYLENE FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-02-28 WO disclosed
WO-2002016681-A1 POLYPROPYLENE FIBERS AND FABRICS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-02-28 WO disclosed
WO-2002016455-A1 POLYPROPYLENE POLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-02-28 WO disclosed
WO-2001046277-A2 POLYPROPYLENE-BASED ADHESIVE COMPOSITIONS EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2001-06-28 WO disclosed
WO-2001036497-A1 SUPPORTED ORGANOMETALLIC CATALYSTS AND THEIR USE IN OLEFIN POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 2001-05-25 WO disclosed
WO-2001032757-A1 FOAMABLE POLYPROPYLENE POLYMERS AND THEIR USE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2001-05-10 WO disclosed
US-6143686-A FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER EXXON CHEMICAL PATENTS, INC. (US) 2000-11-07 US disclosed
US-5965678-A Catalyst system based on monoazadiene metal complexes BAYER AG (DE) 1999-10-12 US disclosed
EP-0889059-A1 Catalyst based on monoazadiene metal complexes BAYER AG (DE) 1999-01-07 EP disclosed