Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 15/20 | 0.59 |
| ▸ | RARB | P10826 | 13/20 | 0.59 |
| ▸ | RXRA | P19793 | 4/20 | 0.59 |
| ▸ | RARA | P10276 | 12/20 | 0.55 |
| ▸ | RXRB | P28702 | 2/20 | 0.50 |
| ▸ | RXRG | P48443 | 2/20 | 0.50 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242401 | 0.79 | RARB (0.55) | RARGRARBRXRARARARXRB | |
| SCHEMBL5846642 | 0.75 | RARB (0.82) | RARGRARBRXRARARARXRB | |
| SCHEMBL5846137 | 0.74 | RARG (0.77) | RARGRARBRXRARARARXRB | |
| SCHEMBL5847006 | 0.73 | RARG (0.74) | RARGRARBRXRARARA | |
| SCHEMBL5847404 | 0.72 | RARG (0.69) | RARGRARBRXRARARA | |
| SCHEMBL8846090 | 0.72 | RARB (0.65) | RARGRARBRXRARARARXRB | |
| SCHEMBL14437917 | 0.72 | RARB (1.00) | RARGRARBRXRARARARXRB | |
| SCHEMBL8674842 | 0.71 | RXRA (0.68) | RARGRARBRXRARARARXRB | |
| SCHEMBL8846040 | 0.71 | PTGER1 (0.64) | RARGRARBRXRARARARXRB | |
| SCHEMBL6243249 | 0.71 | RXRA (0.66) | RARGRARBRXRARARARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005017185-A2 | HEPATOCYTE NUCLEAR FACTOR 4α MODULATOR COMPOUNDS | LIGAND PHARMCEUTICALS INCORPORATED (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005017185-A2 | HEPATOCYTE NUCLEAR FACTOR 4α MODULATOR COMPOUNDS | LIGAND PHARMCEUTICALS INCORPORATED (US) | 2005-02-24 | — | — | WO | disclosed |