Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.40 |
| ▸ | FAP | Q12884 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 4/20 | 0.34 |
| ▸ | CTSS | P25774 | 4/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4040090 | 0.89 | PREP (0.36) | PREPFAPCTSKCTSLCTSS | |
| SCHEMBL4045351 | 0.85 | CTSK (0.44) | PREPFAPSMN1; SMN2CTSKCTSL | |
| SCHEMBL6213754 | 0.83 | CTSK (0.40) | PREPFAPCTSKCTSLCTSS | |
| SCHEMBL6209255 | 0.83 | PREP (0.41) | PREPFAPCTSKCTSLCTSS | |
| SCHEMBL4043416 | 0.83 | CTSK (0.54) | PREPFAPSMN1; SMN2CTSKALDH1A1 | |
| SCHEMBL4039917 | 0.83 | CTSK (0.45) | PREPFAPCTSKCTSLCTSS | |
| SCHEMBL6209147 | 0.82 | CTSK (0.50) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4039168 | 0.82 | CTSK (0.43) | PREPFAPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4042221 | 0.82 | CTSK (0.46) | PREPFAPCTSKCTSLCTSS | |
| SCHEMBL4041462 | 0.82 | CTSK (0.54) | PREPFAPCTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |