Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29041058 | 0.75 | MEN1 (0.50) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL33804 | 0.72 | MAPT (0.55) | KDM4ERECQLALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL6259439 | 0.70 | MAPT (0.53) | KDM4ERECQLALDH1A1MAPTHPGD | |
| SCHEMBL13858360 | 0.70 | PDE1A (0.49) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL4913392 | 0.70 | ALDH1A1 (0.45) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL4914514 | 0.68 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6004377 | 0.68 | KDM4E (0.43) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL1800736 | 0.67 | NPC1 (0.54) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6755862 | 0.67 | KDM4E (0.42) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL13858541 | 0.67 | KDM4E (0.49) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005023209-A1 | AGENT AND METHOD FOR DYEING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-03-17 | — | — | WO | claimed |
| EP-1313434-A1 | OXIDATION DYE | Wella Aktiengesellschaft (DE) | 2003-05-28 | — | — | EP | claimed |
| EP-1257249-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2002-11-20 | — | — | EP | claimed |
| WO-2002069918-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | claimed |
| WO-2002069919-A1 | OXIDATION DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | claimed |
| EP-1586302-A1 | Dye composition comprising at least one pyrazolopyrimidine as oxidation base and at least one 6-alkoxy-2,3-diaminopyridine as coupler | L'OREAL (FR) | 2005-10-19 | — | — | EP | disclosed |
| WO-2005023209-A1 | AGENT AND METHOD FOR DYEING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-03-17 | — | — | WO | disclosed |
| EP-1405628-A1 | Dyeing composition comprising at least one pyrazolopyrimidine oxidation base and at least one 6-alkoxy-2,3-diaminopyrimidine coupler | L'OREAL (FR) | 2004-04-07 | — | — | EP | disclosed |
| EP-1313434-A1 | OXIDATION DYE | Wella Aktiengesellschaft (DE) | 2003-05-28 | — | — | EP | disclosed |
| EP-1257249-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2002-11-20 | — | — | EP | disclosed |
| WO-2002069918-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
| WO-2002069919-A1 | OXIDATION DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |