Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 3/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6755862 | 0.98 | KDM4E (0.42) | KDM4ETSHRHSD17B10MEN1KMT2A | |
| SCHEMBL1801451 | 0.86 | ESR1 (0.43) | KDM4ETSHRHSD17B10MAPTPTGIR | |
| SCHEMBL29041058 | 0.82 | MEN1 (0.50) | KDM4ETSHRMEN1KMT2AMAPT | |
| SCHEMBL33804 | 0.76 | MAPT (0.55) | KDM4EHSD17B10MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL6259439 | 0.74 | MAPT (0.53) | KDM4EHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL4913392 | 0.73 | ALDH1A1 (0.45) | KDM4EHSD17B10KMT2AMAPTCYP1A2 | |
| SCHEMBL4914514 | 0.72 | ALDH1A1 (0.44) | KDM4EHSD17B10MAPTCYP1A2CYP2C9 | |
| SCHEMBL27493933 | 0.71 | CYP1A2 (0.42) | KDM4ETSHRHSD17B10MEN1KMT2A | |
| SCHEMBL1800736 | 0.70 | NPC1 (0.54) | KDM4EMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL13858541 | 0.70 | KDM4E (0.49) | KDM4ETSHRHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257249-B1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AG (DE) | 2006-11-02 | — | — | EP | claimed |
| US-7018426-B2 | Oxidation dye | WELLA AG (DE) | 2006-03-28 | — | — | US | claimed |
| EP-1313434-B1 | OXIDATION DYE | WELLA AG (DE) | 2005-01-12 | — | — | EP | claimed |
| US-6793687-B2 | YELLOW AND ORANGE RANGE COLORING | WELLA AKTIENGESELLSCHAFT (DE) | 2004-09-21 | — | — | US | claimed |
| US-6716257-B2 | OXIDATION DYES, WHICH ARE USED FOR TREATMENT OF HUMAN HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 2004-04-06 | — | — | US | claimed |
| EP-1236460-B1 | Bridged diamino pyrazoles and colouring agents containing them | WELLA AG (DE) | 2003-11-26 | — | — | EP | claimed |
| US-20030159222-A1 | Oxidation dye | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-08-28 | — | — | US | claimed |
| US-20030131423-A1 | Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-17 | — | — | US | claimed |
| US-20020170125-A1 | Bridged diaminopyrazole compounds and dye compositions containing same | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2002-11-21 | — | — | US | claimed |
| EP-1236460-A1 | Bridged diamino pyrazoles and colouring agents containing them | Wella Aktiengesellschaft (DE) | 2002-09-04 | — | — | EP | claimed |
| EP-1257249-B1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AG (DE) | 2006-11-02 | — | — | EP | disclosed |
| US-7018426-B2 | Oxidation dye | WELLA AG (DE) | 2006-03-28 | — | — | US | disclosed |
| EP-1586302-A1 | Dye composition comprising at least one pyrazolopyrimidine as oxidation base and at least one 6-alkoxy-2,3-diaminopyridine as coupler | L'OREAL (FR) | 2005-10-19 | — | — | EP | disclosed |
| EP-1313434-B1 | OXIDATION DYE | WELLA AG (DE) | 2005-01-12 | — | — | EP | disclosed |
| US-6793687-B2 | YELLOW AND ORANGE RANGE COLORING | WELLA AKTIENGESELLSCHAFT (DE) | 2004-09-21 | — | — | US | disclosed |
| EP-1405628-A1 | Dyeing composition comprising at least one pyrazolopyrimidine oxidation base and at least one 6-alkoxy-2,3-diaminopyrimidine coupler | L'OREAL (FR) | 2004-04-07 | — | — | EP | disclosed |
| EP-1236460-B1 | Bridged diamino pyrazoles and colouring agents containing them | WELLA AG (DE) | 2003-11-26 | — | — | EP | disclosed |
| US-20030159222-A1 | Oxidation dye | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-08-28 | — | — | US | disclosed |
| US-20030131423-A1 | Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030159222-A1 | Oxidation dye | KRT18, NOX4, VIM | KDM4E 2382/4885TSHR 4742/4885HSD17B10 765/4885 |
| US-20030131423-A1 | Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives | KRT18, AOC1, PPOX | KDM4E 1906/4885TSHR 4214/4885HSD17B10 1215/4885 |
| US-20020170125-A1 | Bridged diaminopyrazole compounds and dye compositions containing same | ALK, DDC, CBR1 | KDM4E 1827/4885TSHR 3885/4885HSD17B10 583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.