Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240093 | 0.87 | PTGER1 (0.40) | FFAR4SLC1A5RXRAPTGER1PTGER4 | |
| SCHEMBL2988669 | 0.86 | SLC1A5 (0.41) | FFAR4FFAR1SLC1A5HDAC1HDAC2 | |
| SCHEMBL6241365 | 0.83 | SLC1A5 (0.41) | FFAR4FFAR1SLC1A5MCL1RXRA | |
| SCHEMBL6245403 | 0.83 | BCL2L1 (0.39) | MCL1HDAC1HDAC2HDAC8NPC1 | |
| SCHEMBL6240043 | 0.82 | PTGER1 (0.40) | FFAR4SLC1A5RXRAPTGER1PTGER4 | |
| SCHEMBL3001914 | 0.81 | PTGER1 (0.49) | FFAR4FFAR1SLC1A5TP53HTT | |
| SCHEMBL6238928 | 0.80 | BCHE (0.42) | BCHEACHE | |
| SCHEMBL13009909 | 0.79 | PTGER1 (0.58) | RXRAPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL13206902 | 0.79 | PTGER1 (0.48) | SLC1A5RXRANPC1PTGER1PTGER4 | |
| SCHEMBL13009647 | 0.78 | SLC1A5 (0.44) | SLC1A5TP53HDAC1HDAC8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216225-B1 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | BAYER HEALTHCARE AG (DE) | 2005-07-06 | — | — | EP | disclosed |