Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242841 | 0.92 | CYP4F2 (0.44) | BCL2L1MCL1HTR1ABCHEACHE | |
| SCHEMBL6244840 | 0.88 | FFAR4 (0.36) | BCL2L1MCL1APPBCHEACHE | |
| SCHEMBL3775998 | 0.84 | CYP4F2 (0.41) | APPBCHEACHEMAOBTDP1 | |
| SCHEMBL2985237 | 0.84 | ALDH1A1 (0.42) | RAB9AHTR1ABCHEACHEHDAC3 | |
| SCHEMBL6239422 | 0.83 | FFAR4 (0.48) | MCL1NPC1BCHEACHEHDAC1 | |
| SCHEMBL6240093 | 0.82 | PTGER1 (0.40) | APPBCHEACHEMAOB | |
| SCHEMBL2989766 | 0.80 | CYP4F2 (0.41) | NPC1PKMRAB9AHTR1AAPP | |
| SCHEMBL2997165 | 0.78 | CYP4F2 (0.46) | HTR1ABCHEACHEL3MBTL1TDP1 | |
| SCHEMBL6238928 | 0.78 | BCHE (0.42) | BCHEACHEMAOB | |
| SCHEMBL13009576 | 0.77 | CYP4F2 (0.43) | HTR1AMAOBHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216225-B1 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | BAYER HEALTHCARE AG (DE) | 2005-07-06 | — | — | EP | disclosed |