Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 17/20 | 0.59 |
| ▸ | ADAM17 | P78536 | 16/20 | 0.59 |
| ▸ | MMP13 | P45452 | 7/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240147 | 0.87 | ADAM17 (0.72) | MMP1ADAM17MMP13 | |
| SCHEMBL7072312 | 0.87 | ADAM17 (0.72) | MMP1ADAM17MMP13 | |
| SCHEMBL6237873 | 0.85 | ADAM17 (0.61) | MMP1ADAM17MMP13 | |
| SCHEMBL6245036 | 0.85 | MMP1 (0.57) | MMP1ADAM17MMP13 | |
| SCHEMBL6240294 | 0.85 | MMP1 (0.53) | MMP1ADAM17MMP13 | |
| SCHEMBL6241443 | 0.84 | ADAM17 (0.56) | MMP1ADAM17MMP13 | |
| SCHEMBL6239380 | 0.82 | MMP1 (0.58) | MMP1ADAM17MMP13 | |
| SCHEMBL6237689 | 0.79 | ADAM17 (0.67) | MMP1ADAM17MMP13 | |
| SCHEMBL7135335 | 0.79 | ADAM17 (0.67) | MMP1ADAM17MMP13 | |
| SCHEMBL6238209 | 0.76 | MMP1 (0.71) | MMP1ADAM17MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104412-B1 | TACE INHIBITORS | PFIZER PROD INC (US) | 2005-06-15 | — | — | EP | claimed |