Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 7/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 4/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239485 | 0.83 | PTGDR2 (0.66) | PTGDR2IDO1S1PR1KDM4CMRGPRX4 | |
| SCHEMBL17352148 | 0.82 | PPARG (0.50) | SCN9APPARGPPARA | |
| SCHEMBL5505912 | 0.81 | IDO1 (0.60) | PTGDR2IDO1S1PR1MAOBKDM4C | |
| SCHEMBL1508483 | 0.76 | FFAR1 (0.77) | PPARG | |
| SCHEMBL15018384 | 0.75 | MRGPRX4 (0.60) | MRGPRX4 | |
| SCHEMBL7026306 | 0.75 | MAOB (0.74) | MAOBMAOAPPARA | |
| SCHEMBL21944901 | 0.75 | IDO1 (0.56) | PTGDR2IDO1S1PR1MAOBMRGPRX4 | |
| SCHEMBL6242376 | 0.74 | SRD5A2 (0.71) | MAOBMAOAMRGPRX4 | |
| SCHEMBL21945019 | 0.74 | IDO1 (0.55) | PTGDR2IDO1S1PR1MAOBKDM4C | |
| SCHEMBL11229326 | 0.74 | IDO1 (0.62) | PTGDR2IDO1MAOBKDM4CPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |