Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226918 | 0.88 | IDO1 (0.46) | IDO1ALDH1A1PTGDR2NOTUM | |
| SCHEMBL3928139 | 0.80 | MEN1 (0.56) | IDO1ALDH1A1MAPT | |
| SCHEMBL28785033 | 0.79 | IDO1 (0.52) | IDO1KDRKDM4CGPR84PPARG | |
| SCHEMBL11434970 | 0.79 | IDO1 (0.54) | IDO1KDRABCB11GPR84PPARG | |
| SCHEMBL1859313 | 0.77 | IDO1 (1.00) | IDO1GPR84MAOBSLC6A4PYCR1 | |
| SCHEMBL1590516 | 0.76 | RXRA (0.55) | IDO1KDRABCB11PPARGPPARA | |
| SCHEMBL30302148 | 0.76 | RXRA (0.55) | IDO1KDRABCB11PPARGPPARA | |
| SCHEMBL8198450 | 0.75 | ALDH1A1 (0.58) | IDO1ALDH1A1MAOB | |
| SCHEMBL6239485 | 0.75 | PTGDR2 (0.66) | IDO1KDM4CPPARGPPARAPTGDR2 | |
| SCHEMBL932893 | 0.74 | IDO1 (0.61) | IDO1KDRABCB11GPR84NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358606-A | Esters of phenalkyloxycarbonylamino acids | ZOECON CORPORATION (US) | 1982-11-09 | — | — | US | disclosed |