Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.66 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 2/20 | 0.48 |
| ▸ | RXRB | P28702 | 2/20 | 0.48 |
| ▸ | RXRG | P48443 | 2/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1590516 | 0.84 | RXRA (0.55) | PTGDR2IDO1PPARGPPARARXRA | |
| SCHEMBL30302148 | 0.84 | RXRA (0.55) | PTGDR2IDO1PPARGPPARARXRA | |
| SCHEMBL6239486 | 0.83 | PTGDR2 (0.56) | PTGDR2IDO1S1PR1KDM4CPPARG | |
| SCHEMBL5505912 | 0.82 | IDO1 (0.60) | PTGDR2IDO1S1PR1KDM4CPPARG | |
| SCHEMBL10143217 | 0.80 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL15018384 | 0.79 | MRGPRX4 (0.60) | SMN1; SMN2MRGPRX4RXRARXRBRXRG | |
| SCHEMBL1508483 | 0.79 | FFAR1 (0.77) | PPARGFFAR1 | |
| SCHEMBL10143223 | 0.78 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL3498978 | 0.77 | MAOB (0.67) | PTGDR2PPARGPPARAMRGPRX4FFAR1 | |
| SCHEMBL4759196 | 0.77 | FFAR1 (0.77) | PTGDR2S1PR1PPARGPPARAMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |