SCHEMBL6239606

SCHEMBL6239606

CCCCCCCC(C)(c1ccc(O)c(C(C)C)c1)c1ccc(O)c(C(C)C)c1

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 14/20 0.52
CNR2 P34972 14/20 0.52
RORC P51449 1/20 0.49
ESR1 P03372 4/20 0.43
ESR2 Q92731 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8071930 0.88 CNR2 (0.65) CNR1CNR2RORC
SCHEMBL9763865 0.88 RORC (0.54) CNR1CNR2RORCESR1ESR2
SCHEMBL2857428 0.81 ESR1 (0.65) CNR1CNR2ESR1ESR2
SCHEMBL2860135 0.81 ESR1 (0.65) CNR1CNR2ESR1ESR2
SCHEMBL10748415 0.81 ESR1 (0.65) CNR1CNR2ESR1ESR2
SCHEMBL30336860 0.81 ESR1 (0.65) CNR1CNR2ESR1ESR2
SCHEMBL2637888 0.81 RORC (0.57) CNR1CNR2RORCESR1ESR2
SCHEMBL6056720 0.80 ESR1 (0.67) CNR1CNR2ESR1ESR2
SCHEMBL31738904 0.80 ESR1 (0.67) CNR1CNR2ESR1ESR2
SCHEMBL6236779 0.79 ESR1 (0.67) CNR1CNR2ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1274762-B1 POLYCARBONATE PREPARATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2005-05-11 EP disclosed
EP-1274762-A1 POLYCARBONATE PREPARATION PROCESS THE DOW CHEMICAL COMPANY (US) 2003-01-15 EP disclosed
WO-2001077204-A1 POLYCARBONATE PREPARATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2001-10-18 WO disclosed
US-6225436-B1 REACTING PHOSGENE AND DIHYDRIC PHENOL; ADDING ACYL HALIDE; ADDING A CHAIN TERMINATOR TO THE REACTION MIXTURE; COMPLETING POLYMERIZATION REACTION THE DOW CHEMICAL COMPANY 2001-05-01 US disclosed
EP-0941268-A1 POLYCARBONATES THE DOW CHEMICAL COMPANY (US) 1999-09-15 EP disclosed
WO-1998022522-A1 POLYCARBONATES THE DOW CHEMICAL COMPANY (US) 1998-05-28 WO disclosed
US-RE35499-E MOLDED ARTICLES SUCH AS COMPACT DISKS THE DOW CHEMICAL COMPANY (US) 1997-04-29 US disclosed
EP-0699702-A2 Reaction products of carbonyl compounds and dihydric phenols THE DOW CHEMICAL COMPANY (US) 1996-03-06 EP disclosed
US-5128429-A Low temperature block polymerization without randomization RAYCHEM LIMITED (GB) 1992-07-07 US disclosed
EP-0154506-B1 PREPARATION OF ORGANIC POLYMERS RAYCHEM LIMITED (GB) 1992-02-05 EP disclosed
US-4378454-A DETERMINATION OF END-POINT FOR ADDITION OF PHOSGERNE WITH 4-(P-NITROBENZYL)-PYRIDINE THE DOW CHEMICAL COMPANY (US) 1983-03-29 US disclosed
US-4210741-A Phenolphthalein-dihydroxy aromatic compound polycarbonates THE DOW CHEMICAL COMPANY (US) 1980-07-01 US disclosed
US-4195156-A ALKALI METAL SALTS OF DIHYDROXY- BENZENE MONO OR DI SULFONIC ACIDS AS COMONOMERS THE DOW CHEMICAL COMPANY (US) 1980-03-25 US disclosed
US-4168368-A STRESS RESISTANCE THE DOW CHEMICAL COMPANY (US) 1979-09-18 US disclosed
US-4111910-A POLYCARBONATES HAVING CARBAMATE TERMINAL GROUPS THE DOW CHEMICAL COMPANY (US) 1978-09-05 US disclosed
US-4100139-A Polycarbonates incorporating epihalohydrin residues THE DOW CHEMICAL COMPANY (US) 1978-07-11 US disclosed
US-4059566-A Process for controlling the molecular weight of polycarbonates using ammonia or ammonia compounds THE DOW CHEMICAL COMPANY (US) 1977-11-22 US disclosed
US-4055544-A Process for making polycarbonates using ammonia or ammonia compounds as the catalysts THE DOW CHEMICAL COMPANY (US) 1977-10-25 US disclosed
US-4020045-A METALLIC SULFITES THE DOW CHEMICAL COMPANY (US) 1977-04-26 US disclosed
US-3992357-A THERMOPLASTIC THE DOW CHEMICAL COMPANY (US) 1976-11-16 US disclosed