Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242249 | 0.84 | HDAC1 (0.52) | KMT2ATSHRLMNAHDAC3HDAC4 | |
| SCHEMBL6237456 | 0.83 | HDAC1 (0.67) | KMT2ATSHRLMNAMCL1HDAC3 | |
| SCHEMBL6239623 | 0.83 | HDAC1 (0.67) | KMT2ATSHRLMNAMCL1HDAC3 | |
| SCHEMBL398528 | 0.75 | CYP2C9 (0.51) | KMT2ATSHRLMNAHDAC1ALDH1A1 | |
| SCHEMBL398530 | 0.75 | CYP2C9 (0.51) | KMT2ATSHRLMNAHDAC1ALDH1A1 | |
| SCHEMBL18182140 | 0.74 | MEN1 (0.60) | KMT2ATSHRLMNAMAPTMDM2 | |
| SCHEMBL12259104 | 0.74 | MEN1 (0.60) | KMT2ATSHRLMNAMAPTMDM2 | |
| SCHEMBL6240458 | 0.73 | HDAC1 (0.68) | KMT2ATSHRLMNAHDAC3HDAC4 | |
| SCHEMBL1403296 | 0.73 | SNCA (0.61) | KMT2ATSHRLMNAALDH1A1HTT | |
| SCHEMBL6170122 | 0.73 | SNCA (0.61) | KMT2ATSHRLMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011661-A1 | PHARMACEUTICAL AGENTS | UNIVERSITY COLLEGE LONDON (GB) | 2005-02-10 | — | — | WO | claimed |
| WO-2005011661-A1 | PHARMACEUTICAL AGENTS | UNIVERSITY COLLEGE LONDON (GB) | 2005-02-10 | — | — | WO | disclosed |