Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237392 | 0.84 | NPC1 (0.50) | PPARDMAOBFFAR1FFAR4SRD5A2 | |
| SCHEMBL6237724 | 0.80 | MAOB (0.64) | PPARDMAOBFFAR1FFAR4PTGER4 | |
| SCHEMBL9659998 | 0.79 | FFAR1 (0.71) | PPARDMAOBFFAR1FFAR4SRD5A2 | |
| SCHEMBL14966760 | 0.79 | MAOB (0.49) | MAOBPTGER4KDM5AKDM4CKDM5B | |
| SCHEMBL5985 | 0.77 | RXRA (0.51) | PTGDR2RXRARXRBKDM5AKDM4C | |
| SCHEMBL30354629 | 0.77 | RXRA (0.51) | PTGDR2RXRARXRBKDM5AKDM4C | |
| SCHEMBL15978831 | 0.76 | ESR1 (0.42) | PTGDR2MAOBKDM5AKDM4CKDM5B | |
| SCHEMBL23040922 | 0.74 | MAOB (0.51) | MAOB | |
| SCHEMBL10567764 | 0.74 | FFAR1 (0.53) | MAOBFFAR1FFAR4 | |
| SCHEMBL30039160 | 0.74 | MAOB (0.51) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |