Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.64 |
| ▸ | RXRB | P28702 | 7/20 | 0.64 |
| ▸ | RXRG | P48443 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | PARP1 | P09874 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.59 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670382 | 0.91 | SGMS2 (0.60) | ATMPARP1SRD5A2ALDH1A1MAPT | |
| SCHEMBL5393391 | 0.89 | RXRA (0.58) | RXRARXRBRXRGHPGDATM | |
| SCHEMBL10102482 | 0.85 | RXRA (0.68) | RXRARXRBRXRGHPGDATM | |
| SCHEMBL9696207 | 0.82 | SGMS2 (0.66) | PARP1PTGER1FOLH1ALDH1A1MAPT | |
| SCHEMBL7774921 | 0.81 | RXRA (0.58) | RXRARXRBRXRGHPGDPARP1 | |
| SCHEMBL9195711 | 0.79 | MEN1 (0.55) | RXRARXRBRXRGHPGDPTGER1 | |
| SCHEMBL27499066 | 0.79 | SGMS2 (0.84) | RXRARXRBRXRGHPGDALDH1A1 | |
| SCHEMBL4000214 | 0.79 | PTGER1 (0.72) | RXRARXRBRXRGHPGDSRD5A2 | |
| SCHEMBL4728970 | 0.79 | ATM (0.55) | HPGDATMPARP1SRD5A2PTGER1 | |
| SCHEMBL112903 | 0.79 | SGMS2 (0.66) | PARP1PTGER1FOLH1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |