Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.50 |
| ▸ | ITGAL | P20701 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13084159 | 1.00 | ECE1 (0.53) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL4267758 | 0.86 | ECE1 (0.53) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL5493463 | 0.86 | ECE1 (0.53) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL4267759 | 0.86 | ECE1 (0.53) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL468796 | 0.82 | KDM4E (0.57) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL1204312 | 0.82 | KDM4E (0.57) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL468797 | 0.82 | KDM4E (0.57) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL22106724 | 0.81 | ECE1 (0.44) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL14071766 | 0.81 | ECE1 (0.44) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL3510048 | 0.80 | ECE1 (0.50) | ECE1ITGB2ICAM1ITGALCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019177-A1 | AMINOPIPERIDINE AMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | claimed |