Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125543 | 0.84 | ALDH1A3 (0.64) | ALDH1A3KMT2APARP10POLBGLA | |
| SCHEMBL6241127 | 0.81 | KMT2A (0.50) | ALDH1A3KMT2APARP10POLBGLA | |
| SCHEMBL104201 | 0.79 | ALDH1A3 (0.54) | ALDH1A3KMT2APARP10POLBGLA | |
| Hydrogen Peroxide SCHEMBL28902806 | 0.78 | KMT2A (0.70) | ALDH1A3KMT2APARP10POLBGLA | |
| SCHEMBL256381 | 0.77 | ALDH1A3 (0.52) | ALDH1A3KMT2APARP10POLBGLA | |
| SCHEMBL197284 | 0.76 | ALDH1A3 (0.56) | ALDH1A3KMT2APARP10POLBGLA | |
| SCHEMBL6282894 | 0.76 | ALDH1A3 (0.56) | ALDH1A3KMT2APARP10POLBGLA | |
| SCHEMBL1239857 | 0.75 | KMT2A (0.40) | KMT2APOLBALDH1A1MAPTMEN1 | |
| SCHEMBL153796 | 0.75 | ALDH1A3 (0.50) | ALDH1A3KMT2APARP10POLBGLA | |
| SCHEMBL25218457 | 0.75 | ACHE (0.41) | KMT2APOLBALDH1A1MAPTNLRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005010028-A1 | ALPHA-AMINO ACID BENZOTHIAZOLYLTHIO ESTER AS INTERMEDIATES FOR MANUFACTURE OF ACE INHIBITORS AND PROCESS FOR PREPARATION THEREOF | LUPIN LIMITED (IN) | 2005-02-03 | — | — | WO | claimed |
| WO-2005010028-A1 | ALPHA-AMINO ACID BENZOTHIAZOLYLTHIO ESTER AS INTERMEDIATES FOR MANUFACTURE OF ACE INHIBITORS AND PROCESS FOR PREPARATION THEREOF | LUPIN LIMITED (IN) | 2005-02-03 | — | — | WO | disclosed |
| EP-0015079-B1 | HALOGENATING COMPOUNDS AND A PROCESS FOR THEIR PRODUCTION | ELI LILLY AND COMPANY (US) | 1987-09-09 | — | — | EP | disclosed |
| EP-0014567-B1 | PROCESSES FOR PREPARATION OF BETA-LACTAM COMPOUNDS | ELI LILLY AND COMPANY (US) | 1984-01-18 | — | — | EP | disclosed |
| EP-0015080-B1 | PROCESS FOR THE STABILIZATION OF HALOGENATING COMPOUND AND STABILIZED HALOGENATING COMPOSITIONS | ELI LILLY AND COMPANY (US) | 1983-07-13 | — | — | EP | disclosed |
| EP-0014566-B1 | HALOGENATED BETA-LACTAM COMPOUNDS AND PROCESS FOR THEIR PREPARATION | ELI LILLY AND COMPANY (US) | 1983-05-25 | — | — | EP | disclosed |
| US-4271305-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4240988-A | WITH TERTIARY AMINE BASES OR HALIDE COMPLEXING AGENTS | ELI LILLY AND COMPANY (US) | 1980-12-23 | — | — | US | disclosed |
| US-4230644-A | DERIVED FROM TRIARYL PHOSPHITES AND CHLORINE OR BROMINE | ELI LILLY AND COMPANY (US) | 1980-10-28 | — | — | US | disclosed |
| US-4226986-A | 7-ACYLAMINO-3-HYDROXY-3-CEPHEM COMPOUND, TRIARYL PHOSPHITE DIHALIDE | ELI LILLY AND COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| US-4223133-A | USING A TRIARYL PHOSPHITE-HALOGEN COMPLEX | ELI LILLY AND COMPANY (US) | 1980-09-16 | — | — | US | disclosed |
| EP-0015080-A1 | Process for the stabilization of halogenating compound and stabilized halogenating compositions | ELI LILLY AND COMPANY (US) | 1980-09-03 | — | — | EP | disclosed |
| EP-0015079-A1 | Halogenating compounds and a process for their production | ELI LILLY AND COMPANY (US) | 1980-09-03 | — | — | EP | disclosed |
| EP-0014567-A1 | Processes for preparation of beta-lactam compounds | ELI LILLY AND COMPANY (US) | 1980-08-20 | — | — | EP | disclosed |
| EP-0014566-A1 | Halogenated beta-lactam compounds and process for their preparation | ELI LILLY AND COMPANY (US) | 1980-08-20 | — | — | EP | disclosed |
| US-4211702-A | TRIARYLPHOSPHITE-HALOGEN COMPLEX HALOGENATING AGENT | ELI LILLY AND COMPANY (US) | 1980-07-08 | — | — | US | disclosed |