SCHEMBL6241908

SCHEMBL6241908

NN1Cc2c(ccc3ccccc23)S1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
HSD17B10 Q99714 4/20 0.38
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
CYP2A6 P11509 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HPRT1 P00492 1/20 0.35
ANPEP P15144 1/20 0.34
CYP1A2 P05177 2/20 0.33
HPGD P15428 2/20 0.33
GLA P06280 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP1B1 Q16678 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2215560 0.79 KDM4E (0.38) KDM4EMAPTHSD17B10ALDH1A1TSHR
SCHEMBL6241131 0.76 ALDH1A1 (0.40) KDM4EMAPTHSD17B10ALDH1A1TSHR
SCHEMBL9784311 0.67 HSD17B10 (0.46) KDM4EMAPTHSD17B10ALDH1A1TSHR
SCHEMBL6185179 0.65 RYR2 (0.36) KDM4EALDH1A1HPGDKMT2A
SCHEMBL14983740 0.64 ALDH1A1 (0.44) KDM4EMAPTHSD17B10ALDH1A1TSHR
SCHEMBL30726708 0.64 ALDH1A1 (0.44) KDM4EMAPTHSD17B10ALDH1A1TSHR
SCHEMBL926548 0.64 HSD17B10 (0.42) KDM4EMAPTHSD17B10ALDH1A1TSHR
SCHEMBL5699226 0.63 HSD17B10 (0.41) KDM4EMAPTHSD17B10ALDH1A1TSHR
SCHEMBL3076762 0.62 HSD17B10 (0.39) KDM4EMAPTHSD17B10ALDH1A1TSHR
SCHEMBL137986 0.61 ALDH1A1 (0.43) KDM4EMAPTHSD17B10ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1072614-B1 Method for polymerizing vinyl monomers in a coated reactor SHINETSU CHEMICAL CO (JP) 2005-07-06 EP disclosed
EP-0900800-B1 Stabilizer for organic borate salts and photosensitive composition containing the same SHOWA DENKO KK (JP) 2003-12-03 EP disclosed
US-6562543-B2 Comprising a compound having one or two nitrogen-containing 5-or 6- membered heterocyclic ring having a double bond within the ring, a primary, secondary, or tertiary amino compound, or a mercapto compound; heat stability SHOWA DENKO K.K. (JP) 2003-05-13 US disclosed
EP-0934955-B1 Polymerization process characterized by a two layer coating against scale formation deposited using a steam carrier SHINETSU CHEMICAL CO (JP) 2003-04-16 EP disclosed
EP-0540143-B1 Compounds and methods for inhibition of HIV and related viruses MEDIVIR AB (SE) 2003-02-05 EP disclosed
US-6362291-B1 PRETREATING VESSEL HAS ANTIDEPOSIT COATING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-03-26 US disclosed
US-6335403-B1 ANTISCALING AGENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-01-01 US disclosed
US-20010046643-A1 Stabilizer for organic borate salts and photosensitive composition containing the same OGATA TOMONARI (JP) 2001-11-29 US disclosed
US-6320001-B1 COATING INNER WALL SURFACES WITH A POLYMER SCALE PREVENTIVE FILM OF AN AROMATIC OR HETEROCYCLIC COMPOUND HAVING 5 OR MORE CONJUGATED PI BONDS DYE AND/OR PIGMENT ON THE FIRST LAYER AND A SECOND LAYER OF A DYE AND/OR PIGMENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-11-20 US disclosed
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
EP-0540143-A2 Compounds and methods for inhibition of HIV and related viruses Medivir Aktiebolag (SE) 1993-05-05 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0084208-B1 ASYMMETRIC DICHROIC DYE MOLECULES HAVING POLYAZOARYL LINKING GROUPS AND SUBSTITUTED ARYL THIAZYL SUBSTITUENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-11-26 EP disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
US-4565424-A Asymmetric dichroic dye molecules having poly(arylazo) linking groups, a bis-substituted aryl thiazyl end group, and another end group MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-01-21 US disclosed
EP-0084208-A2 Asymmetric dichroic dye molecules having polyazoaryl linking groups and substituted aryl thiazyl substituents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-07-27 EP disclosed
EP-0003141-A2 Process for the preparation of 2-amino-arylenothiazole compounds and their ring N-substituted derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1979-07-25 EP disclosed
US-4153343-A Liquid crystal dyestuffs and electro-optic devices incorporating same RCA CORPORATION (US) 1979-05-08 US disclosed