Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654272 | 0.78 | MAPT (0.43) | MAPTALDH1A1HSD17B10POLBKDM4E | |
| SCHEMBL28060146 | 0.75 | MAPT (0.55) | MAPTALDH1A1HSD17B10POLBKDM4E | |
| SCHEMBL20210937 | 0.75 | TDP1 (0.33) | ALDH1A1TDP1TSHR | |
| SCHEMBL7090657 | 0.75 | ALDH1A1 (0.36) | MAPTALDH1A1HSD17B10POLBKDM4E | |
| Hydrochloric Acid SCHEMBL16862196 | 0.73 | MAPT (0.48) | MAPTALDH1A1HSD17B10POLBKDM4E | |
| SCHEMBL460054 | 0.72 | TDP1 (0.38) | MAPTALDH1A1HSD17B10POLBKDM4E | |
| SCHEMBL28196248 | 0.72 | POLB (0.37) | MAPTALDH1A1HSD17B10POLBKDM4E | |
| SCHEMBL9793008 | 0.72 | MAPT (0.52) | MAPTALDH1A1HSD17B10POLBKDM4E | |
| SCHEMBL6678290 | 0.71 | ALDH1A1 (0.32) | ALDH1A1TDP1TSHR | |
| Hydrochloric Acid SCHEMBL9793078 | 0.71 | MAPT (0.50) | MAPTALDH1A1HSD17B10POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279329-A | Composition for dyeing hair comprising ultra-efficient high water multi-layer emulsion system and process for preparing the same | 酷姆国际公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-111603403-A | Gradual hair color compositions and methods of use thereof | 酷姆国际公司 | 2020-09-01 | — | — | CN | disclosed |
| CN-105492078-A | Method for evaluating hair color change | UNILEVER NV | 2016-04-13 | — | — | CN | disclosed |
| WO-2005002533-A1 | HAIR DYEING METHOD INCLUDING AN ALIGNING STEP | UNILEVER PLC (GB) | 2005-01-13 | — | — | WO | disclosed |
| US-6200353-B1 | Coupler for use in oxidative hair dyeing | BRISTOL MYERS SQUIBB COMPANY | 2001-03-13 | — | — | US | disclosed |