Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5395480 | 0.81 | CES2 (0.65) | CES2CES1HDAC1LCKFYN | |
| SCHEMBL13906392 | 0.81 | CES2 (0.46) | CES2CES1HDAC1LCKFYN | |
| SCHEMBL5057415 | 0.78 | ALDH1A1 (0.46) | CES2CES1KDM4ETSHRALDH1A1 | |
| SCHEMBL12462328 | 0.76 | — | — | |
| SCHEMBL1133332 | 0.76 | LCK (0.61) | CES2CES1HDAC1LCKFYN | |
| SCHEMBL236021 | 0.76 | — | — | |
| SCHEMBL5958448 | 0.75 | CES2 (0.47) | CES2CES1HDAC1LCKFYN | |
| SCHEMBL8672795 | 0.75 | CES2 (0.56) | CES2CES1HDAC1LCKFYN | |
| SCHEMBL1384047 | 0.75 | CES2 (0.56) | CES2CES1HDAC1LCKFYN | |
| Hydrochloric Acid SCHEMBL27579964 | 0.75 | CES2 (0.56) | CES2CES1HDAC1LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103145692-B | Preparation method of 4, 5-dihydro-6H-cyclopenta[b]thiophene-6-ketone | YANCHENG INST TECHNOLOGY | 2014-07-16 | — | — | CN | claimed |
| CN-103145692-A | Preparation method of 4, 5-dihydro-6H-cyclopenta[b]thiophene-6-ketone | YANCHENG INST TECHNOLOGY | 2013-06-12 | — | — | CN | claimed |
| CN-103145692-B | Preparation method of 4, 5-dihydro-6H-cyclopenta[b]thiophene-6-ketone | YANCHENG INST TECHNOLOGY | 2014-07-16 | — | — | CN | disclosed |
| CN-103145692-A | Preparation method of 4, 5-dihydro-6H-cyclopenta[b]thiophene-6-ketone | YANCHENG INST TECHNOLOGY | 2013-06-12 | — | — | CN | disclosed |
| WO-2005019177-A1 | AMINOPIPERIDINE AMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |
| US-5017723-A | Psychotropic Agents | JOUVEINAL S.A. (FR) | 1991-05-21 | — | — | US | disclosed |