Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 11/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542004 | 0.94 | ADRB3 (0.38) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL6804979 | 0.87 | HSD11B1 (0.36) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL4463534 | 0.82 | ADRB3 (0.49) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4463530 | 0.82 | ADRB3 (0.49) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6239352 | 0.76 | ADRB3 (0.42) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4472057 | 0.76 | ADRB3 (0.45) | ADRB3ADRB1ADRB2BACE1 | |
| SCHEMBL4472051 | 0.76 | ADRB3 (0.45) | ADRB3ADRB1ADRB2BACE1 | |
| SCHEMBL4465920 | 0.74 | GLI1 (0.47) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4465914 | 0.74 | GLI1 (0.47) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4463297 | 0.73 | ADRB3 (0.45) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546086-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004002939-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-08 | — | — | WO | disclosed |