Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 11/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242580 | 0.94 | ADRB3 (0.42) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL6804979 | 0.93 | HSD11B1 (0.36) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL6239352 | 0.81 | ADRB3 (0.42) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4465914 | 0.79 | GLI1 (0.47) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4465920 | 0.79 | GLI1 (0.47) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4463297 | 0.78 | ADRB3 (0.45) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4463304 | 0.78 | ADRB3 (0.45) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4472391 | 0.76 | ADRB3 (0.47) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4478737 | 0.76 | ADRB3 (0.51) | ADRB3ADRB1 | |
| SCHEMBL4478735 | 0.76 | ADRB3 (0.51) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010074-A1 | ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS BETA-3-ADRENOCEPTOR AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-05-27 | — | — | WO | disclosed |